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Basic information

CohesinDB ID: CDBP00415606

Locus: chr21-26958780-26959264

Data sourse: GSE206145, GSE116344

Cell type: RH4, HEK293T

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 40% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 37%, "14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, SMARCA2, NME2, XBP1, FOXA1, CHD7, MORC2, HDAC3, MYOG, TEAD1, ETV1, OCA2, CTCF, MNT, GATA6, TEAD4, KMT2B, PDX1, TFAP2C, POU2F2, NANOG, MYCN, POU5F1, TOP2A, DUX4, BAHD1, ERG, MYC, SMARCA4, RAD21, GRHL3, GABPA, STAT3, NKX3-1, ARNTL, NR3C1, CEBPB, CREB1, EZH2, SPI1, GATA2, SIX2, FLI1, MYF5, RUNX1, ZNF534, SMARCC1, ZNF384, GATA4, GR, ARNT, SOX11, ATF2, MAFB, CDK8, MED1, MYB, MAFK, REST, HOXA9, FOXP1, PAX7, FOXA2, SS18, FOXF1, MEF2C, HOXB13, RELA, NEUROD1, ISL1, HIF1A, OTX2, GATA3, MAX, HAND2, NEUROG2, TCF7L2, ZNF334, MYOD1, PHOX2B, PAX3-FOXO1, AR, EGLN2, NOTCH3, BRD4, JUND, TBX2, AHR

Target gene symbol (double-evidenced CRMs): LINC00113,ADAMTS5,ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 6

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736, ENSG00000225298,

eachgene

Deatailed information for cohesin site CDBP00415606