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Basic information

CohesinDB ID: CDBP00415662

Locus: chr21-27202334-27203054

Data sourse: GSE138405, GSE206145-NatGen2015

Cell type: Hela-Kyoto, Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 39% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 92%, "5_TxWk": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: AR, FOXO1, NR3C1, PGR, GATA2, FOXA2, MYCN, GATA4, PIAS1, CHD7, ESR1, FOXA1, FOXF1, GATA3, STAT3, NUP98-HOXA9, TWIST1

Target gene symbol (double-evidenced CRMs): ADAMTS1,LINC00113,ADAMTS5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 10

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736, ENSG00000225298,

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Deatailed information for cohesin site CDBP00415662