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Basic information

CohesinDB ID: CDBP00415663

Locus: chr21-27206351-27206965

Data sourse: ENCSR000BLD, ENCSR000BLY, GSE105028, GSE206145, GSE83726, GSE138105, GSE116344, GSE97394

Cell type: RPE, H1-hESC, RH4, SLK, H9-hESC, SK-N-SH, HUES64

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: Mau2,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 39% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 79%, "7_Enh": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NANOG, SMARCA2, POU5F1, SOX2, XBP1, RUNX2, CHD7, RAD21, HIF1A, CBFB, ATF2, GATA3, STAT3, PBX3, MED1, NR3C1, ETV1, TP53, OCA2, MYOD1, EBF3, TCF12, EP300, BCL11A, REST, RXR, ASH2L, BRD4, JUND, TEAD4, MYF5

Target gene symbol (double-evidenced CRMs): LINC00113,ADAMTS5,ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 10

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736, ENSG00000225298,

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Deatailed information for cohesin site CDBP00415663