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Basic information

CohesinDB ID: CDBP00415665

Locus: chr21-27212637-27214873

Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE126634, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE111537, GSE25021, GSE108869, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE138405, GSE206145-NatGen2015, GSE135093, ENCSR198ZYJ, GSE138105, GSE130135, GSE116344, GSE106870, GSE145327, ENCSR000EHW, GSE85526, ENCSR000ECE, GSE206145, ENCSR000EHX, GSE97394, GSE105004, ENCSR000HPG, ENCSR000EDE, GSE68388, GSE126990, ENCSR000ECS

Cell type: RH4, SLK, CVB-hiPSC, Liver, HuCC-T1, H9-hESC, RPE, Fibroblast, HEKn, Ishikawa, HeLa-S3, IMR-90, H1-hESC, SK-N-SH, HUES64, MCF-7, Hela-Kyoto, HEK293T, Neurons-H1, HeLa, OCI-AML-3, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 19% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.744

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 39% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 90%, "5_TxWk": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: GATA3, CEBPB, GATA2

Target gene symbol (double-evidenced CRMs): ADAMTS1,ADAMTS5,LINC00113

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 11

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736, ENSG00000225298,

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Deatailed information for cohesin site CDBP00415665