Browse_each

Basic information

CohesinDB ID: CDBP00415667

Locus: chr21-27218751-27221382

Data sourse: GSE206145, ENCSR000BTU, GSE206145-NatGen2015, ENCSR000HPG

Cell type: RPE, Ishikawa, Fibroblast, IMR-90

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: NIPBL,SA1,Rad21,SA2,Mau2,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 39% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 69%, "7_Enh": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, FOXA2, EZH2phosphoT487, SRF, RELA, JUNB, RUNX2, NFIC, MYC, RAD21, GRHL3, GATA3, BATF3, BATF, STAT3, PBX3, FOXM1, MAX, FOS, MED1, NR3C1, CEBPB, NCOA3, CEBPD, ESR1, NFKB1, JUN, TCF12, EP300, NCOR1, BRD4, JUND, TEAD4, BRCA1, FOSL2

Target gene symbol (double-evidenced CRMs): LINC00113,ADAMTS1,ADAMTS5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 19

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736, ENSG00000225298,

eachgene

Deatailed information for cohesin site CDBP00415667