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Basic information

CohesinDB ID: CDBP00415669

Locus: chr21-27224651-27225725

Data sourse: GSE138405, GSE206145, GSE206145-NatGen2015, GSE126990, GSE165895

Cell type: RPE, Hela-Kyoto, Fibroblast, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 39% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 81%, "7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, POU2F2, MAFG, FOXA2, ZNF496, LDB1, TOP2A, SOX2, NME2, XBP1, DUX4, FOXA1, CDK9, HOXB13, SMARCC1, ERG, CREBBP, ZNF384, JUNB, RUNX2, BRG1, ISL1, GRHL3, ZNF487, OTX2, GATA3, GABPA, PBX3, FOS, NFE2, HAND2, MED1, NR3C1, CEBPB, NR2F2, TEAD1, TCF7L2, NFE2L2, PHOX2B, JUN, NUP98-HOXA9, CTCF, EP300, AR, PAX8, GATA2, ZHX1, BRD4, JUND, CLOCK, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): ADAMTS1,LINC00113,ADAMTS5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 7

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736, ENSG00000225298,

Tools:

Assay

refGene

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Cohesin site CDBP00415669

CDBP00415669 regulated genes

Related cohesin loop

Deatailed information for cohesin site CDBP00415669

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