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Basic information

CohesinDB ID: CDBP00415687

Locus: chr21-27299811-27301698

Data sourse: ENCSR000EFJ, ENCSR000HPG, GSE206145-NatGen2015, GSE126755, GSE165895

Cell type: Fibroblast, Neutrophil, IMR-90, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 83%, "5_TxWk": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ARNT, FOXA1, BATF3, FOXF1, BRD2

Target gene symbol (double-evidenced CRMs): ADAMTS1,LINC00113,ADAMTS5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 20

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736, ENSG00000225298,

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Deatailed information for cohesin site CDBP00415687