- Basic information
- CohesinDB ID: CDBP00415688
- Locus: chr21-27302530-27302899
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Data sourse: GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 89%,
"5_TxWk": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, PAX7, ZNF384, NR3C1, MED1, AR, RUNX2, BCL11A, HNRNPUL1, XBP1, ZBTB48, SCRT1, FOXA1, SPI1, PRDM9, SMARCC1, AHR
- Target gene symbol (double-evidenced CRMs): ADAMTS5,LINC00113,ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000154736,
ENSG00000225298,
- Related loop:
chr21:26850000-26875000~~chr21:27300000-27325000,
chr21:26875000-26900000~~chr21:27300000-27325000,
chr21:26925000-26950000~~chr21:27300000-27325000,
chr21:27050000-27075000~~chr21:27300000-27325000,
chr21:27100000-27125000~~chr21:27300000-27325000,
chr21:27200000-27225000~~chr21:27300000-27325000,
chr21:27300000-27325000~~chr21:27425000-27450000,
chr21:27300000-27325000~~chr21:27450000-27475000,
chr21:27300000-27325000~~chr21:27475000-27500000,
chr21:27300000-27325000~~chr21:27550000-27575000,
chr21:27300000-27325000~~chr21:27675000-27700000,
chr21:27300000-27325000~~chr21:27700000-27725000,
chr21:27300000-27325000~~chr21:28200000-28225000,
chr21:27300000-27325000~~chr21:28225000-28250000,
chr21:27300000-27325000~~chr21:28325000-28350000,
chr21:27300000-27325000~~chr21:28725000-28750000,