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Basic information

CohesinDB ID: CDBP00415689

Locus: chr21-27305606-27308114

Data sourse: GSE206145-NatGen2015, GSE67783, GSE165895

Cell type: Fibroblast, HSPC, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 78%, "7_Enh": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, FOXA2, SOX2, GTF2B, DUX4, FOXF1, FOXA1, HOXB13, SMARCC1, ERG, RELA, RUNX2, PRDM1, GRHL3, STAT3, MED1, NR3C1, CEBPB, NR2F2, SPI1, HNF4A, GATA2, BRD4

Target gene symbol (double-evidenced CRMs): ADAMTS5,ADAMTS1,LINC00113

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 35

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736, ENSG00000225298,

eachgene

Deatailed information for cohesin site CDBP00415689