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Basic information

CohesinDB ID: CDBP00415690

Locus: chr21-27315387-27315916

Data sourse: ENCSR000BLD, ENCSR000BTU, ENCSR000EFJ, GSE67783, GSE138405, ENCSR000BLY, GSE105028, GSE206145-NatGen2015, ENCSR000ECE, GSE50893, ENCSR000EHX, GSE83726, GSE116344, GSE97394, GSE108869, GSE94872

Cell type: H1-hESC, Fibroblast, Hela-Kyoto, RH4, GM2610, Ishikawa, HUVEC, HeLa-S3, HUES64, IMR-90, SK-N-SH, HSPC, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.856

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 81%, "9_Het": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, CEBPA, CRY1, KDM4C, ZFX, POU4F2, XBP1, STAT1, FOXA1, ZNF823, ERG, RELA, RUNX2, CDK6, RAD21, GABPA, TAL1, ZNF143, EZH2, LMO2, OCA2, MED26, USF2, CTCF, AR, GATA2, NOTCH3, SMC3, TFAP2C

Target gene symbol (double-evidenced CRMs): ADAMTS1,LINC00113,ADAMTS5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736, ENSG00000225298,

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Deatailed information for cohesin site CDBP00415690