- Basic information
- CohesinDB ID: CDBP00415701
- Locus: chr21-27363618-27364538
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Data sourse: ENCSR000EHW, GSE206145-NatGen2015, ENCSR000EHX, ENCSR000BLY
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Cell type: Fibroblast, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 90%,
"5_TxWk": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXM1, NR3C1, MEF2A, SOX2, TEAD4, NFE2L2, SIN3A, RAD21, JUND, GATA3, PBX3, TCF12, EP300, NFE2, FOSL2
- Target gene symbol (double-evidenced CRMs): ADAMTS1,ADAMTS5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000154736,
- Related loop:
chr21:26850000-26875000~~chr21:27350000-27375000,
chr21:26950000-26975000~~chr21:27350000-27375000,
chr21:27100000-27125000~~chr21:27350000-27375000,
chr21:27225000-27250000~~chr21:27350000-27375000,
chr21:27350000-27375000~~chr21:27500000-27525000,
chr21:27350000-27375000~~chr21:27550000-27575000,
chr21:27350000-27375000~~chr21:27675000-27700000,
chr21:27350000-27375000~~chr21:28325000-28350000,
chr21:27350000-27375000~~chr21:28725000-28750000,
chr21:27361572-27363261~~chr21:27564032-27565789,
chr21:27361581-27363364~~chr21:27563988-27566020,