- Basic information
- CohesinDB ID: CDBP00415726
- Locus: chr21-27464634-27465158
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Data sourse: GSE206145-NatGen2015
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Cell type: Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 94%,
"14_ReprPCWk": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMARCA2, FOXA2, SMAD3, FOXA1, BAHD1, HOXC5, RELA, GATA4, LHX2, PBX4, GATA3, STAT3, PBX3, TP63, FOS, TEAD1, KLF6, GRHL2, TCF12, GATA2, BRD4
- Target gene symbol (double-evidenced CRMs): ADAMTS1,ADAMTS5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000154736,
- Related loop:
chr21:26848761-26852116~~chr21:27465346-27467252,
chr21:26850000-26875000~~chr21:27450000-27475000,
chr21:26880869-26882702~~chr21:27465683-27467004,
chr21:26950000-26975000~~chr21:27450000-27475000,
chr21:27100000-27125000~~chr21:27450000-27475000,
chr21:27200000-27225000~~chr21:27450000-27475000,
chr21:27225000-27250000~~chr21:27450000-27475000,
chr21:27300000-27325000~~chr21:27450000-27475000,
chr21:27450000-27475000~~chr21:27550000-27575000,
chr21:27450000-27475000~~chr21:27675000-27700000,
chr21:27450000-27475000~~chr21:28325000-28350000,
chr21:27450000-27475000~~chr21:28725000-28750000,