- Basic information
- CohesinDB ID: CDBP00415727
- Locus: chr21-27465427-27465909
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Data sourse: GSE67783, GSE86191, GSE111913, GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast, HCT-116, RT-112, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 94%,
"9_Het": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZBTB48, TRP47, RELA, RUNX2
- Target gene symbol (double-evidenced CRMs): ADAMTS1,ADAMTS5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000154736,
- Related loop:
chr21:26848761-26852116~~chr21:27465346-27467252,
chr21:26850000-26875000~~chr21:27450000-27475000,
chr21:26880869-26882702~~chr21:27465683-27467004,
chr21:26950000-26975000~~chr21:27450000-27475000,
chr21:27100000-27125000~~chr21:27450000-27475000,
chr21:27200000-27225000~~chr21:27450000-27475000,
chr21:27225000-27250000~~chr21:27450000-27475000,
chr21:27300000-27325000~~chr21:27450000-27475000,
chr21:27450000-27475000~~chr21:27550000-27575000,
chr21:27450000-27475000~~chr21:27675000-27700000,
chr21:27450000-27475000~~chr21:28325000-28350000,
chr21:27450000-27475000~~chr21:28725000-28750000,