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Basic information

CohesinDB ID: CDBP00415728

Locus: chr21-27466171-27466657

Data sourse: ENCSR000BLD, ENCSR000BTU, ENCSR000EFJ, ENCSR230ZWH, GSE138405, ENCSR000HPG, ENCSR000BLY, GSE105028, GSE206145-NatGen2015, ENCSR000ECE, GSE50893, GSE103477, GSE145327, GSE108869, GSE94872, GSE97394

Cell type: GM2630, H1-hESC, Fibroblast, Hela-Kyoto, GM2610, Ishikawa, HUVEC, GM2588, HeLa-S3, HUES64, IMR-90, SK-N-SH, Liver, THP-1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.833

Subunit: SMC3,Rad21,SA2,SA1

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 94%, "9_Het": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOS, NR3C1, CEBPB, BCL6, POU5F1, MYB, RAD21, ZSCAN16, BRD4, JUND, JUN, FOXA1, BATF3, BATF, ZNF205, SMC3, CTCF, ZNF143, SPI1

Target gene symbol (double-evidenced CRMs): ADAMTS5,ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736,

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Deatailed information for cohesin site CDBP00415728