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Basic information

CohesinDB ID: CDBP00415752

Locus: chr21-27557265-27557849

Data sourse: GSE206145-NatGen2015

Cell type: Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 95%, "5_TxWk": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, FOXO1, NANOG, FOXA2, EZH2phosphoT487, ERF, FOXA1, HOXB13, HNF4G, ERG, RELA, CDK2, RUNX2, BRG1, EOMES, GABPA, TAL1, NKX3-1, ZNF10, HDAC3, TLE3, NR3C1, CREB1, PIAS1, TBX5, BAF155, EP300, AR, GATA6, HDAC2, GATA2, ARID1A, ASH2L, FOXP1, ZNF528

Target gene symbol (double-evidenced CRMs): LTN1,LINC00113,ADAMTS5,ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 10

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736, ENSG00000225298, ENSG00000198862,

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Deatailed information for cohesin site CDBP00415752