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Basic information

CohesinDB ID: CDBP00415754

Locus: chr21-27563002-27566992

Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE126634, GSE116868, GSE132649, GSE25021, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, ENCSR330ELC, ENCSR000EDW, GSE108869, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE115602, ENCSR000DZP, ENCSR000EAC, GSE165895, ENCSR000BKV, GSE115250, GSE122299, GSE138405, GSE93080, GSE76893, GSE101921, GSE135093, GSE152721, GSE206145-NatGen2015, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, ENCSR703TNG, GSE106870, GSE116344, GSE138105, GSE145327, GSE94872, ENCSR000EEG, GSE76815, GSE98367, ENCSR193NSH, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE155828, ENCSR000ECE, ENCSR981FDC, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, ENCSR767DFK, GSE62063, GSE85526, GSE97394, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR956LGB, GSE55407, GSE110061, GSE129526, ENCSR000HPG, ENCSR000EDE, GSE68388, GSE206145, GSE126990, GSE50893, ENCSR000ECS, GSE131577

Cell type: MDM, RH4, GM2610, SLK, CVB-hiPSC, GM19240, CVI-hiPSC, Liver, Transformed-RPE1, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, HMEC, Fibroblast, HEKn, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, DKO, HFFc6, H1-hESC, SNYDER, MB157, GM12878, GM12891, GM2588, SK-N-SH, GM19239, HeLa-Tet-On, THP-1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, T-47D, A-549, HUVEC, HCAEC, Ramos, HeLa, TC-71, OCI-AML-3, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 52% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.356

Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 70%, "5_TxWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF384, FOXA1, KDM1A, FOXA2

Target gene symbol (double-evidenced CRMs): ADAMTS1,LTN1,ADAMTS5,LINC00113

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 38

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736, ENSG00000225298, ENSG00000198862,

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Deatailed information for cohesin site CDBP00415754