- Basic information
- CohesinDB ID: CDBP00415755
- Locus: chr21-27567650-27574605
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Data sourse: ENCSR000EFJ, GSE105004, ENCSR230ZWH, GSE67783, GSE98367, GSE138405, GSE165895, ENCSR000HPG, GSE206145, GSE101921, GSE135093, GSE85526, GSE120943, GSE206145-NatGen2015, GSE68388, GSE138105, GSE83726, GSE116344, GSE80989, ENCSR917QNE
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Cell type: RPE, Macrophage, HMEC, Hela-Kyoto, Fibroblast, Monocytes, HEKn, RH4, SLK, VU1199-F, HeLa, IMR-90, Liver, HSPC, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 15% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.822
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,ESCO2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 51%,
"7_Enh": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, HOXB13, GATA2, FOXA2, ASH2L, ARNT, HNF1B, DUX4, FOXP1, FOXA1, NCOR2, BAF155
- Target gene symbol (double-evidenced CRMs): LINC00113,ADAMTS1,LTN1,ADAMTS5
- Function elements
- Human SNPs: Response_to_cytidine_analogues_(gemcitabine)
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 69
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000154736,
ENSG00000225298,
ENSG00000198862,
- Related loop:
chr21:26825000-26850000~~chr21:27550000-27575000,
chr21:26848648-26851445~~chr21:27564056-27565671,
chr21:26848655-26851362~~chr21:27563683-27565992,
chr21:26848657-26851571~~chr21:27563649-27565742,
chr21:26848663-26851399~~chr21:27564063-27565968,
chr21:26848686-26851632~~chr21:27563536-27566212,
chr21:26848735-26851318~~chr21:27564094-27565665,
chr21:26848739-26851655~~chr21:27563988-27566020,
chr21:26848748-26851651~~chr21:27563895-27566084,
chr21:26848751-26851646~~chr21:27563920-27566182,
chr21:26848757-26851632~~chr21:27563925-27566163,
chr21:26848770-26851390~~chr21:27564032-27565789,
chr21:26848785-26851026~~chr21:27564188-27565622,
chr21:26848834-26851460~~chr21:27563907-27565665,
chr21:26848936-26851075~~chr21:27564009-27565590,
chr21:26848947-26851347~~chr21:27564022-27565633,
chr21:26849043-26851569~~chr21:27564132-27565614,
chr21:26849049-26852110~~chr21:27564063-27565789,
chr21:26850000-26875000~~chr21:27550000-27575000,
chr21:26850000-26875000~~chr21:27575000-27600000,
chr21:26875000-26900000~~chr21:27550000-27575000,
chr21:26880663-26882691~~chr21:27564041-27565758,
chr21:26880713-26882657~~chr21:27563683-27565992,
chr21:26880766-26882640~~chr21:27563925-27566163,
chr21:26880869-26882702~~chr21:27564068-27565806,
chr21:26900000-26925000~~chr21:27550000-27575000,
chr21:26909548-26910893~~chr21:27564129-27565802,
chr21:26925000-26950000~~chr21:27550000-27575000,
chr21:26950000-26975000~~chr21:27550000-27575000,
chr21:26963690-26966148~~chr21:27563536-27566212,
chr21:26975000-27000000~~chr21:27550000-27575000,
chr21:27025000-27050000~~chr21:27550000-27575000,
chr21:27050000-27075000~~chr21:27550000-27575000,
chr21:27075000-27100000~~chr21:27550000-27575000,
chr21:27100000-27125000~~chr21:27550000-27575000,
chr21:27200000-27225000~~chr21:27550000-27575000,
chr21:27225000-27250000~~chr21:27550000-27575000,
chr21:27250000-27275000~~chr21:27550000-27575000,
chr21:27300000-27325000~~chr21:27550000-27575000,
chr21:27325000-27350000~~chr21:27550000-27575000,
chr21:27350000-27375000~~chr21:27550000-27575000,
chr21:27361572-27363261~~chr21:27564032-27565789,
chr21:27361581-27363364~~chr21:27563988-27566020,
chr21:27375000-27400000~~chr21:27550000-27575000,
chr21:27450000-27475000~~chr21:27550000-27575000,
chr21:27476178-27477767~~chr21:27563649-27565742,
chr21:27550000-27575000~~chr21:27675000-27700000,
chr21:27550000-27575000~~chr21:27700000-27725000,
chr21:27550000-27575000~~chr21:28025000-28050000,
chr21:27550000-27575000~~chr21:28050000-28075000,
chr21:27550000-27575000~~chr21:28225000-28250000,
chr21:27550000-27575000~~chr21:28325000-28350000,
chr21:27550000-27575000~~chr21:28375000-28400000,
chr21:27550000-27575000~~chr21:28425000-28450000,
chr21:27550000-27575000~~chr21:28525000-28550000,
chr21:27550000-27575000~~chr21:28725000-28750000,
chr21:27550000-27575000~~chr21:28925000-28950000,
chr21:27563559-27566226~~chr21:28334487-28338171,
chr21:27564022-27565753~~chr21:27699929-27702131,
chr21:27564022-27565753~~chr21:28050923-28052951,