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Basic information

CohesinDB ID: CDBP00415769

Locus: chr21-27671283-27676296

Data sourse: ENCSR000EFJ, GSE67783, GSE111913, ENCSR000HPG, GSE206145, GSE85526, GSE206145-NatGen2015, GSE165895

Cell type: RPE, Fibroblast, HEKn, IMR-90, RT-112, HSPC, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 66%, "7_Enh": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: SOX2, POU2F2, HIF1A

Target gene symbol (double-evidenced CRMs): ADAMTS1,ADAMTS5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 50

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736,

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Deatailed information for cohesin site CDBP00415769