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Basic information

CohesinDB ID: CDBP00415771

Locus: chr21-27679599-27679830

Data sourse: GSE206145-NatGen2015, GSE86191

Cell type: Fibroblast, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 80%, "9_Het": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, POU2F2, ZSCAN5D, MYCN, SS18, ZFX, FOXA1, CDK9, HOXB13, ERG, RELA, CREBBP, MYC, RUNX2, BRG1, LHX2, GRHL3, SP140, OTX2, GABPA, PAX5, TP63, NKX3-1, HDAC3, ARNTL, TLE3, NR3C1, CEBPB, ETV1, PIAS1, CREB1, EZH2, LMO2, ESR1, TP53, ZNF680, GRHL2, JUN, BAF155, AR, HDAC2, GATA2, ARID1A, ASH2L, BRD4, FOXP1, MAZ, HCFC1R1, SMC3

Target gene symbol (double-evidenced CRMs): ADAMTS5,ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736,

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Deatailed information for cohesin site CDBP00415771