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Basic information

CohesinDB ID: CDBP00415772

Locus: chr21-27680983-27682358

Data sourse: GSE138405, ENCSR000HPG, GSE206145-NatGen2015, GSE126990, GSE165895

Cell type: Hela-Kyoto, Fibroblast, IMR-90, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,SMC3,SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 80%, "7_Enh": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, NANOG, BCL6, FOXA2, POU5F1, TOP2A, TEAD4, SMAD3, FOXA1, HOXB13, HNF4G, ERG, RELA, JUNB, RUNX2, GATA4, RAD21, PBX4, GATA3, TAL1, PBX3, STAT3, NKX3-1, FOS, TLE3, NR3C1, CEBPB, TEAD1, CREB1, PIAS1, OCA2, SETDB1, JUN, TCF12, BAF155, AR, GATA2, ARID1A, HSF1, BRD4, JUND, FOXP1, SMC3, FOSL2

Target gene symbol (double-evidenced CRMs): ADAMTS1,ADAMTS5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 11

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736,

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Deatailed information for cohesin site CDBP00415772