- Basic information
- CohesinDB ID: CDBP00415779
- Locus: chr21-27722043-27722380
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Data sourse: ENCSR000BTU, GSE108869, GSE68388, GSE138105
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Cell type: Ishikawa, SLK, HeLa-S3, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 87%,
"7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU5F1, TOP2A, ZFX, DUX4, FOXA1, ERG, CREBBP, NFIC, PBX4, HIF1A, NFIB, STAT3, FOS, RCOR1, CDX2, KLF4, NR3C1, CEBPB, KLF5, NR2F2, TEAD1, ELF3, TCF12, USF1, EP300, SPI1, HNF4A, AR, GATA6, YAP1, BRD4, TEAD4, NCOR2
- Target gene symbol (double-evidenced CRMs): ADAMTS5,LINC00113,ADAMTS1,LTN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000154736,
ENSG00000225298,
ENSG00000198862,
- Related loop:
chr21:25600000-25625000~~chr21:27700000-27725000,
chr21:26750000-26775000~~chr21:27700000-27725000,
chr21:26825000-26850000~~chr21:27700000-27725000,
chr21:26850000-26875000~~chr21:27700000-27725000,
chr21:26950000-26975000~~chr21:27700000-27725000,
chr21:27025000-27050000~~chr21:27700000-27725000,
chr21:27200000-27225000~~chr21:27700000-27725000,
chr21:27300000-27325000~~chr21:27700000-27725000,
chr21:27550000-27575000~~chr21:27700000-27725000,
chr21:27700000-27725000~~chr21:28025000-28050000,
chr21:27700000-27725000~~chr21:28050000-28075000,
chr21:27700000-27725000~~chr21:28325000-28350000,
chr21:27700000-27725000~~chr21:28500000-28525000,
chr21:27700000-27725000~~chr21:28725000-28750000,
chr21:27700000-27725000~~chr21:28925000-28950000,
chr21:27725000-27750000~~chr21:28025000-28050000,
chr21:27725000-27750000~~chr21:28325000-28350000,