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Basic information

CohesinDB ID: CDBP00415925

Locus: chr21-28325514-28326311

Data sourse: ENCSR000BLD, ENCSR000BTU, GSE105028, GSE68388, GSE97394, GSE64758

Cell type: H1-hESC, Ishikawa, H9-hESC, HuCC-T1, HUES64

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: NIPBL,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 35% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 75%, "9_Het": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, NANOG, MAFG, ZNF207, POU5F1, SOX2, XBP1, MAFF, SMAD3, JUN, FOXA1, HOXB13, ERG, KDM1A, RELA, USP7, JUNB, NFIC, EOMES, BRG1, RAD21, TOP1, CHD7, ARNT, MORC2, ATF2, STAT3, FOXM1, MAX, NKX3-1, FOS, LEF1, MED1, TLE3, KLF4, CEBPB, NR3C1, CREB1, PIAS1, ETV1, EZH2, SNAI2, C11orf30, SETDB1, NFKB1, T, TCF12, USF1, BAF155, MAFK, EP300, NIPBL, AR, CTCF, SP1, HDAC2, GATA2, ARID1A, E2F6, NOTCH3, BRD4, CTBP2, BCOR, FOXP1, JUND, SCRT1, TEAD4, ZNF316

Target gene symbol (double-evidenced CRMs): ADAMTS5,LTN1,ADAMTS1,LINC00113

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000154734, ENSG00000154736, ENSG00000225298, ENSG00000198862,

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Deatailed information for cohesin site CDBP00415925