- Basic information
- CohesinDB ID: CDBP00415927
- Locus: chr21-28341277-28341586
-
Data sourse: GSE206145, GSE206145-NatGen2015
-
Cell type: RPE, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 94%,
"5_TxWk": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: .
- Target gene symbol (double-evidenced CRMs): ADAMTS5,LINC00113,ADAMTS1,LTN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000154736,
ENSG00000225298,
ENSG00000198862,
- Related loop:
chr21:25600000-25625000~~chr21:28325000-28350000,
chr21:26750000-26775000~~chr21:28325000-28350000,
chr21:26825000-26850000~~chr21:28325000-28350000,
chr21:26850000-26875000~~chr21:28325000-28350000,
chr21:26900000-26925000~~chr21:28325000-28350000,
chr21:26950000-26975000~~chr21:28325000-28350000,
chr21:27050000-27075000~~chr21:28325000-28350000,
chr21:27100000-27125000~~chr21:28325000-28350000,
chr21:27175000-27200000~~chr21:28325000-28350000,
chr21:27200000-27225000~~chr21:28325000-28350000,
chr21:27250000-27275000~~chr21:28325000-28350000,
chr21:27300000-27325000~~chr21:28325000-28350000,
chr21:27350000-27375000~~chr21:28325000-28350000,
chr21:27450000-27475000~~chr21:28325000-28350000,
chr21:27475000-27500000~~chr21:28325000-28350000,
chr21:27550000-27575000~~chr21:28325000-28350000,
chr21:27563559-27566226~~chr21:28334487-28338171,
chr21:27675000-27700000~~chr21:28325000-28350000,
chr21:27699511-27702311~~chr21:28334487-28338171,
chr21:27699913-27702170~~chr21:28333968-28338137,
chr21:27699929-27702131~~chr21:28335562-28338194,
chr21:27699952-27702148~~chr21:28335622-28338264,
chr21:27700000-27725000~~chr21:28325000-28350000,
chr21:27700023-27702186~~chr21:28335622-28338100,
chr21:27700279-27702131~~chr21:28335654-28338236,
chr21:27700281-27702128~~chr21:28335610-28338190,
chr21:27700291-27702152~~chr21:28335560-28338076,
chr21:27700318-27702132~~chr21:28334564-28338188,
chr21:27700355-27702199~~chr21:28335663-28338245,
chr21:27700525-27701999~~chr21:28335697-28338238,
chr21:27703438-27704690~~chr21:28334487-28338171,
chr21:27725000-27750000~~chr21:28325000-28350000,
chr21:27750000-27775000~~chr21:28325000-28350000,
chr21:27758254-27761457~~chr21:28334487-28338171,
chr21:27758272-27760733~~chr21:28335606-28338251,
chr21:27758346-27760171~~chr21:28335560-28338076,
chr21:27758357-27760293~~chr21:28333968-28338137,
chr21:27758367-27760680~~chr21:28335663-28338245,
chr21:27758404-27760678~~chr21:28335576-28338198,
chr21:27758494-27760671~~chr21:28335562-28338194,
chr21:27758638-27760649~~chr21:28335622-28338264,
chr21:27775000-27800000~~chr21:28325000-28350000,
chr21:27802121-27804049~~chr21:28335748-28338250,
chr21:27825000-27850000~~chr21:28325000-28350000,
chr21:28017763-28020776~~chr21:28333968-28338137,
chr21:28050000-28075000~~chr21:28325000-28350000,
chr21:28050939-28053207~~chr21:28335622-28338264,
chr21:28051032-28053224~~chr21:28335606-28338251,
chr21:28051084-28053207~~chr21:28334487-28338171,
chr21:28051112-28052927~~chr21:28335663-28338245,
chr21:28075000-28100000~~chr21:28325000-28350000,
chr21:28096589-28098118~~chr21:28335562-28338194,
chr21:28100000-28125000~~chr21:28325000-28350000,
chr21:28110675-28112671~~chr21:28335622-28338264,
chr21:28175000-28200000~~chr21:28325000-28350000,
chr21:28225000-28250000~~chr21:28325000-28350000,
chr21:28325000-28350000~~chr21:28425000-28450000,
chr21:28325000-28350000~~chr21:28500000-28525000,
chr21:28325000-28350000~~chr21:28525000-28550000,
chr21:28325000-28350000~~chr21:28575000-28600000,
chr21:28325000-28350000~~chr21:28625000-28650000,
chr21:28325000-28350000~~chr21:28725000-28750000,
chr21:28325000-28350000~~chr21:28900000-28925000,
chr21:28325000-28350000~~chr21:28925000-28950000,
chr21:28325000-28350000~~chr21:42850000-42875000,
chr21:28333968-28338137~~chr21:28744250-28746679,
chr21:28334487-28338171~~chr21:28521160-28523346,
chr21:28334487-28338171~~chr21:28741591-28743796,
chr21:28334487-28338171~~chr21:28744475-28746618,
chr21:28334487-28338171~~chr21:28791723-28794424,
chr21:28335536-28338216~~chr21:28744455-28746667,
chr21:28335562-28338194~~chr21:28744431-28746621,
chr21:28335581-28338353~~chr21:28744361-28746655,
chr21:28335605-28338376~~chr21:28744204-28746655,
chr21:28335606-28338251~~chr21:28741590-28743829,
chr21:28335606-28338251~~chr21:28744395-28746552,
chr21:28335622-28338100~~chr21:28744200-28746589,
chr21:28335654-28338236~~chr21:28742147-28743465,
chr21:28335654-28338236~~chr21:28744469-28746575,
chr21:28335663-28338245~~chr21:28741981-28743659,
chr21:28335663-28338245~~chr21:28744452-28746493,
chr21:28335721-28338216~~chr21:28744497-28746545,
chr21:28335803-28338280~~chr21:28744453-28746446,
chr21:28338312-28339715~~chr21:28521324-28523315,
chr21:28338312-28339715~~chr21:28744452-28746493,