- Basic information
- CohesinDB ID: CDBP00416022
- Locus: chr21-28734874-28735184
-
Data sourse: GSE111913
-
Cell type: RT-112
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: SA1,SA2,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 73%,
"5_TxWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, CTNNB1, ZFX, MAFF, ZNF30, FOXA1, HLF, ERG, NFIC, GATA4, TCF4, HIF1A, NKX2-1, TP63, FOS, MITF, CDX2, KLF4, CEBPB, MAF, ZNF506, TRIM28, TFAP2C, TCF7L2, NR1H2, ESR1, TP53, JUN, MAFK, HNF4A, AR, JUND, ZIM3, AHR
- Target gene symbol (double-evidenced CRMs): ADAMTS1,LINC00113,ADAMTS5,LTN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000154736,
ENSG00000225298,
ENSG00000198862,
- Related loop:
chr21:25600000-25625000~~chr21:28725000-28750000,
chr21:25875000-25900000~~chr21:28725000-28750000,
chr21:26175000-26200000~~chr21:28725000-28750000,
chr21:26700000-26725000~~chr21:28725000-28750000,
chr21:26725000-26750000~~chr21:28725000-28750000,
chr21:26750000-26775000~~chr21:28725000-28750000,
chr21:26800000-26825000~~chr21:28725000-28750000,
chr21:26825000-26850000~~chr21:28725000-28750000,
chr21:26850000-26875000~~chr21:28725000-28750000,
chr21:26950000-26975000~~chr21:28725000-28750000,
chr21:27200000-27225000~~chr21:28725000-28750000,
chr21:27300000-27325000~~chr21:28725000-28750000,
chr21:27325000-27350000~~chr21:28725000-28750000,
chr21:27350000-27375000~~chr21:28725000-28750000,
chr21:27450000-27475000~~chr21:28725000-28750000,
chr21:27475000-27500000~~chr21:28725000-28750000,
chr21:27550000-27575000~~chr21:28725000-28750000,
chr21:27600000-27625000~~chr21:28725000-28750000,
chr21:27675000-27700000~~chr21:28725000-28750000,
chr21:27700000-27725000~~chr21:28725000-28750000,
chr21:27750000-27775000~~chr21:28725000-28750000,
chr21:27775000-27800000~~chr21:28725000-28750000,
chr21:27800000-27825000~~chr21:28725000-28750000,
chr21:28025000-28050000~~chr21:28725000-28750000,
chr21:28050000-28075000~~chr21:28725000-28750000,
chr21:28075000-28100000~~chr21:28725000-28750000,
chr21:28100000-28125000~~chr21:28725000-28750000,
chr21:28175000-28200000~~chr21:28725000-28750000,
chr21:28200000-28225000~~chr21:28725000-28750000,
chr21:28225000-28250000~~chr21:28725000-28750000,
chr21:28325000-28350000~~chr21:28725000-28750000,
chr21:28350000-28375000~~chr21:28725000-28750000,
chr21:28375000-28400000~~chr21:28725000-28750000,
chr21:28425000-28450000~~chr21:28725000-28750000,
chr21:28500000-28525000~~chr21:28725000-28750000,
chr21:28525000-28550000~~chr21:28725000-28750000,
chr21:28550000-28575000~~chr21:28725000-28750000,
chr21:28575000-28600000~~chr21:28725000-28750000,
chr21:28625000-28650000~~chr21:28725000-28750000,
chr21:28725000-28750000~~chr21:28925000-28950000,