- Basic information
- CohesinDB ID: CDBP00416024
- Locus: chr21-28739033-28739334
-
Data sourse: ENCSR230ZWH, ENCSR917QNE
-
Cell type: Liver
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 69%,
"5_TxWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NFIA, PGR, HMG20A, SOX2, XBP1, FOXA1, NFIC, RUNX3, CHD7, TP63, TEAD1, ESR1, TCF12, BAF155, SOX5, IRF4, SMC1, TEAD4, FOXA3, GLIS1, POU2F2, POU5F1, HOXC5, ERG, MYC, HOMEZ, RAD21, RXRA, NKX2-1, BATF3, GABPA, NKX3-1, NR3C1, STAT5B, GRHL2, SPI1, GATA2, ZNF644, NCOA2, RUNX1, CBX1, SIN3A, SOX13, ZFX, SMAD3, PRDM10, MEF2A, CREBBP, RUNX2, GATA4, NFIB, PBX4, ARNT, SOX11, PBX3, MED1, TEAD3, PIAS1, TBX5, NKX2-5, REST, ASH2L, FOXP1, STAG1, FOXA2, ZBTB33, CDK9, HOXB13, KDM1A, RELA, HIF1A, OTX2, GATA3, TAL1, MAX, NRIP1, ZNF143, HAND2, NR2F2, KDM5B, PKNOX1, PHOX2B, AR, EGLN2, HSF1, NCOR1, JUND, BRD4, AHR
- Target gene symbol (double-evidenced CRMs): ADAMTS5,ADAMTS1,LTN1,LINC00113
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000154736,
ENSG00000225298,
ENSG00000198862,
- Related loop:
chr21:25600000-25625000~~chr21:28725000-28750000,
chr21:25875000-25900000~~chr21:28725000-28750000,
chr21:26175000-26200000~~chr21:28725000-28750000,
chr21:26700000-26725000~~chr21:28725000-28750000,
chr21:26725000-26750000~~chr21:28725000-28750000,
chr21:26750000-26775000~~chr21:28725000-28750000,
chr21:26800000-26825000~~chr21:28725000-28750000,
chr21:26825000-26850000~~chr21:28725000-28750000,
chr21:26850000-26875000~~chr21:28725000-28750000,
chr21:26950000-26975000~~chr21:28725000-28750000,
chr21:27200000-27225000~~chr21:28725000-28750000,
chr21:27300000-27325000~~chr21:28725000-28750000,
chr21:27325000-27350000~~chr21:28725000-28750000,
chr21:27350000-27375000~~chr21:28725000-28750000,
chr21:27450000-27475000~~chr21:28725000-28750000,
chr21:27475000-27500000~~chr21:28725000-28750000,
chr21:27550000-27575000~~chr21:28725000-28750000,
chr21:27600000-27625000~~chr21:28725000-28750000,
chr21:27675000-27700000~~chr21:28725000-28750000,
chr21:27700000-27725000~~chr21:28725000-28750000,
chr21:27750000-27775000~~chr21:28725000-28750000,
chr21:27758303-27760306~~chr21:28744310-28746641,
chr21:27758346-27760171~~chr21:28744222-28746677,
chr21:27758357-27760293~~chr21:28744250-28746679,
chr21:27775000-27800000~~chr21:28725000-28750000,
chr21:27800000-27825000~~chr21:28725000-28750000,
chr21:28018798-28020167~~chr21:28741954-28743601,
chr21:28025000-28050000~~chr21:28725000-28750000,
chr21:28050000-28075000~~chr21:28725000-28750000,
chr21:28050094-28052904~~chr21:28744171-28746673,
chr21:28050942-28052908~~chr21:28744204-28746655,
chr21:28050985-28053261~~chr21:28744200-28746589,
chr21:28051112-28052927~~chr21:28741981-28743659,
chr21:28051197-28052726~~chr21:28744207-28746569,
chr21:28075000-28100000~~chr21:28725000-28750000,
chr21:28096733-28098046~~chr21:28741591-28743796,
chr21:28100000-28125000~~chr21:28725000-28750000,
chr21:28175000-28200000~~chr21:28725000-28750000,
chr21:28200000-28225000~~chr21:28725000-28750000,
chr21:28225000-28250000~~chr21:28725000-28750000,
chr21:28325000-28350000~~chr21:28725000-28750000,
chr21:28333968-28338137~~chr21:28744250-28746679,
chr21:28334487-28338171~~chr21:28741591-28743796,
chr21:28335605-28338376~~chr21:28744204-28746655,
chr21:28335606-28338251~~chr21:28741590-28743829,
chr21:28335622-28338100~~chr21:28744200-28746589,
chr21:28335654-28338236~~chr21:28742147-28743465,
chr21:28335663-28338245~~chr21:28741981-28743659,
chr21:28350000-28375000~~chr21:28725000-28750000,
chr21:28375000-28400000~~chr21:28725000-28750000,
chr21:28425000-28450000~~chr21:28725000-28750000,
chr21:28500000-28525000~~chr21:28725000-28750000,
chr21:28516060-28518025~~chr21:28742005-28743432,
chr21:28516094-28518223~~chr21:28744204-28746655,
chr21:28516260-28517994~~chr21:28744214-28746632,
chr21:28516268-28518070~~chr21:28744329-28746608,
chr21:28516335-28518256~~chr21:28744250-28746679,
chr21:28516349-28517977~~chr21:28744171-28746673,
chr21:28516366-28517998~~chr21:28744241-28746558,
chr21:28516366-28518040~~chr21:28744325-28746663,
chr21:28516369-28518093~~chr21:28744334-28746652,
chr21:28516385-28518004~~chr21:28744246-28746649,
chr21:28516389-28518036~~chr21:28742004-28743407,
chr21:28516405-28518026~~chr21:28744207-28746569,
chr21:28516412-28518000~~chr21:28741981-28743659,
chr21:28516422-28518049~~chr21:28744175-28746644,
chr21:28516435-28517898~~chr21:28744281-28746569,
chr21:28516480-28517852~~chr21:28744326-28746557,
chr21:28516496-28517982~~chr21:28744207-28746688,
chr21:28516504-28517958~~chr21:28744313-28746546,
chr21:28516509-28517821~~chr21:28744324-28746498,
chr21:28525000-28550000~~chr21:28725000-28750000,
chr21:28550000-28575000~~chr21:28725000-28750000,
chr21:28575000-28600000~~chr21:28725000-28750000,
chr21:28625000-28650000~~chr21:28725000-28750000,
chr21:28725000-28750000~~chr21:28925000-28950000,
chr21:28744171-28746673~~chr21:28939367-28941312,
chr21:28744250-28746679~~chr21:28939349-28941136,
chr21:28744313-28746546~~chr21:28939599-28941068,
chr21:28744325-28746663~~chr21:28939368-28941287,