- Basic information
- CohesinDB ID: CDBP00416027
- Locus: chr21-28750506-28751239
-
Data sourse: GSE67783, ENCSR230ZWH, GSE206145, GSE206145-NatGen2015, ENCSR917QNE
-
Cell type: RPE, Liver, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 78%,
"5_TxWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXA2, CEBPA, CHD2, ZFX, FOXA1, HOXB13, YY1, ZNF384, OGG1, NEUROD1, NFIC, RAD21, GRHL3, RXRA, OTX2, GATA3, RCOR1, MED1, CEBPG, CEBPB, NR2F2, ZMYM3, ZNF334, TBX5, TCF12, SP1, HNF4A, AR, RBM25, BRD4, ZNF92
- Target gene symbol (double-evidenced CRMs): LTN1,ADAMTS1,ADAMTS5
- Function elements
- Human SNPs: Pulse_pressure
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000154736,
ENSG00000198862,
- Related loop:
chr21:25600000-25625000~~chr21:28725000-28750000,
chr21:25725000-25750000~~chr21:28750000-28775000,
chr21:25875000-25900000~~chr21:28725000-28750000,
chr21:26175000-26200000~~chr21:28725000-28750000,
chr21:26700000-26725000~~chr21:28725000-28750000,
chr21:26725000-26750000~~chr21:28725000-28750000,
chr21:26750000-26775000~~chr21:28725000-28750000,
chr21:26800000-26825000~~chr21:28725000-28750000,
chr21:26825000-26850000~~chr21:28725000-28750000,
chr21:26825000-26850000~~chr21:28750000-28775000,
chr21:26850000-26875000~~chr21:28725000-28750000,
chr21:26850000-26875000~~chr21:28750000-28775000,
chr21:26950000-26975000~~chr21:28725000-28750000,
chr21:26950000-26975000~~chr21:28750000-28775000,
chr21:27200000-27225000~~chr21:28725000-28750000,
chr21:27300000-27325000~~chr21:28725000-28750000,
chr21:27325000-27350000~~chr21:28725000-28750000,
chr21:27350000-27375000~~chr21:28725000-28750000,
chr21:27450000-27475000~~chr21:28725000-28750000,
chr21:27475000-27500000~~chr21:28725000-28750000,
chr21:27550000-27575000~~chr21:28725000-28750000,
chr21:27600000-27625000~~chr21:28725000-28750000,
chr21:27675000-27700000~~chr21:28725000-28750000,
chr21:27700000-27725000~~chr21:28725000-28750000,
chr21:27750000-27775000~~chr21:28725000-28750000,
chr21:27758254-27761457~~chr21:28744475-28746618,
chr21:27758303-27760306~~chr21:28744310-28746641,
chr21:27758346-27760171~~chr21:28744222-28746677,
chr21:27758357-27760293~~chr21:28744250-28746679,
chr21:27758727-27759929~~chr21:28744528-28746609,
chr21:27775000-27800000~~chr21:28725000-28750000,
chr21:27800000-27825000~~chr21:28725000-28750000,
chr21:28018790-28020175~~chr21:28744431-28746621,
chr21:28018816-28020167~~chr21:28744361-28746655,
chr21:28018902-28020084~~chr21:28744451-28746563,
chr21:28025000-28050000~~chr21:28725000-28750000,
chr21:28050000-28075000~~chr21:28725000-28750000,
chr21:28050094-28052904~~chr21:28744171-28746673,
chr21:28050923-28052951~~chr21:28744431-28746621,
chr21:28050939-28053207~~chr21:28744399-28746641,
chr21:28050942-28052908~~chr21:28744204-28746655,
chr21:28050985-28053261~~chr21:28744200-28746589,
chr21:28050991-28052838~~chr21:28744455-28746667,
chr21:28051112-28052922~~chr21:28744497-28746545,
chr21:28051112-28052927~~chr21:28744452-28746493,
chr21:28051170-28052632~~chr21:28744510-28746501,
chr21:28051197-28052726~~chr21:28744207-28746569,
chr21:28051210-28052762~~chr21:28744462-28746595,
chr21:28075000-28100000~~chr21:28725000-28750000,
chr21:28100000-28125000~~chr21:28725000-28750000,
chr21:28175000-28200000~~chr21:28725000-28750000,
chr21:28200000-28225000~~chr21:28725000-28750000,
chr21:28225000-28250000~~chr21:28725000-28750000,
chr21:28325000-28350000~~chr21:28725000-28750000,
chr21:28333968-28338137~~chr21:28744250-28746679,
chr21:28334487-28338171~~chr21:28744475-28746618,
chr21:28335536-28338216~~chr21:28744455-28746667,
chr21:28335562-28338194~~chr21:28744431-28746621,
chr21:28335581-28338353~~chr21:28744361-28746655,
chr21:28335605-28338376~~chr21:28744204-28746655,
chr21:28335606-28338251~~chr21:28744395-28746552,
chr21:28335622-28338100~~chr21:28744200-28746589,
chr21:28335654-28338236~~chr21:28744469-28746575,
chr21:28335663-28338245~~chr21:28744452-28746493,
chr21:28335721-28338216~~chr21:28744497-28746545,
chr21:28335803-28338280~~chr21:28744453-28746446,
chr21:28338312-28339715~~chr21:28744452-28746493,
chr21:28350000-28375000~~chr21:28725000-28750000,
chr21:28375000-28400000~~chr21:28725000-28750000,
chr21:28425000-28450000~~chr21:28725000-28750000,
chr21:28500000-28525000~~chr21:28725000-28750000,
chr21:28516094-28518223~~chr21:28744204-28746655,
chr21:28516110-28518054~~chr21:28744361-28746655,
chr21:28516260-28517994~~chr21:28744214-28746632,
chr21:28516268-28518070~~chr21:28744329-28746608,
chr21:28516305-28518150~~chr21:28744396-28746610,
chr21:28516312-28518065~~chr21:28744462-28746595,
chr21:28516335-28518256~~chr21:28744250-28746679,
chr21:28516349-28517977~~chr21:28744171-28746673,
chr21:28516366-28517998~~chr21:28744241-28746558,
chr21:28516366-28518040~~chr21:28744325-28746663,
chr21:28516367-28517967~~chr21:28744528-28746609,
chr21:28516369-28518093~~chr21:28744334-28746652,
chr21:28516385-28518004~~chr21:28744246-28746649,
chr21:28516389-28518036~~chr21:28744431-28746621,
chr21:28516405-28518026~~chr21:28744207-28746569,
chr21:28516422-28518049~~chr21:28744175-28746644,
chr21:28516435-28517898~~chr21:28744281-28746569,
chr21:28516442-28517932~~chr21:28744495-28746431,
chr21:28516448-28517941~~chr21:28744483-28746572,
chr21:28516451-28517995~~chr21:28744497-28746545,
chr21:28516480-28517852~~chr21:28744326-28746557,
chr21:28516482-28517966~~chr21:28744423-28746593,
chr21:28516496-28517982~~chr21:28744207-28746688,
chr21:28516499-28517905~~chr21:28744483-28746431,
chr21:28516500-28517883~~chr21:28744479-28746534,
chr21:28516504-28517958~~chr21:28744313-28746546,
chr21:28516509-28517821~~chr21:28744324-28746498,
chr21:28516517-28517884~~chr21:28744494-28746441,
chr21:28516537-28517911~~chr21:28744386-28746621,
chr21:28516541-28517884~~chr21:28744431-28746530,
chr21:28518143-28519542~~chr21:28744431-28746621,
chr21:28525000-28550000~~chr21:28725000-28750000,
chr21:28550000-28575000~~chr21:28725000-28750000,
chr21:28575000-28600000~~chr21:28725000-28750000,
chr21:28625000-28650000~~chr21:28725000-28750000,
chr21:28725000-28750000~~chr21:28925000-28950000,
chr21:28744171-28746673~~chr21:28939367-28941312,
chr21:28744250-28746679~~chr21:28939349-28941136,
chr21:28744313-28746546~~chr21:28939599-28941068,
chr21:28744325-28746663~~chr21:28939368-28941287,
chr21:28744395-28746552~~chr21:28939371-28941595,
chr21:28744396-28746610~~chr21:28939355-28941613,
chr21:28744399-28746641~~chr21:28939435-28941573,
chr21:28744431-28746621~~chr21:28939400-28941106,
chr21:28744452-28746493~~chr21:28939378-28941094,
chr21:28744455-28746667~~chr21:28939164-28941280,
chr21:28744475-28746618~~chr21:28938688-28941630,
chr21:28744498-28746544~~chr21:28939448-28940997,
chr21:28750000-28775000~~chr21:28900000-28925000,
chr21:28750000-28775000~~chr21:28925000-28950000,
chr21:28750000-28775000~~chr21:31075000-31100000,