- Basic information
- CohesinDB ID: CDBP00416030
- Locus: chr21-28763422-28763635
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Data sourse: ENCSR153HNT, GSE98367
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Cell type: K-562, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 80%,
"5_TxWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, NME2, HNF1A, XBP1, FOXA1, NFIC, ZBTB44, PRDM1, TRIM28, ETV1, ESR1, MED26, CTCF, TCF12, EP300, BAF155, GATA6, PAX8, TEAD4, PDX1, EED, NANOG, ZNF778, CTBP1, ERF, DUX4, ZBTB48, ERG, GABPA, NKX3-1, ARNTL, NR3C1, CEBPB, CREB1, EZH2, SPI1, GATA2, SIX2, RUNX1, SMC1A, NKX2-2, LDB1, CRY1, ZFX, ERG3, RUNX2, GATA4, OSR2, FOXM1, PBX3, MAFB, FOS, MED1, SCRT2, PIAS1, TBX5, NKX2-5, REST, OVOL3, ARID1A, ASH2L, FOXP1, PRDM6, FOXA2, SS18, GTF2B, FOXF1, ZNF574, ZNF823, ZNF580, HOXB13, YY1, RELA, HIF1A, GATA3, TAL1, MAX, ZNF143, GATA1, TLE3, TCF7L2, AR, PAX3-FOXO1, BRD4, SCRT1, JUND, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): LTN1,ADAMTS5,ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000154736,
ENSG00000198862,
- Related loop:
chr21:25725000-25750000~~chr21:28750000-28775000,
chr21:26825000-26850000~~chr21:28750000-28775000,
chr21:26850000-26875000~~chr21:28750000-28775000,
chr21:26950000-26975000~~chr21:28750000-28775000,
chr21:28750000-28775000~~chr21:28900000-28925000,
chr21:28750000-28775000~~chr21:28925000-28950000,
chr21:28750000-28775000~~chr21:31075000-31100000,