Deatailed information for cohesin site CDBP00416145

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  • Basic information
  • CohesinDB ID: CDBP00416145
  • Locus: chr21-29174072-29177013
  • Data sourse: GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR501LQA, ENCSR000BLY, ENCSR150EFU, GSE25021, ENCSR330ELC, ENCSR000EDW, GSE108869, ENCSR917QNE, ENCSR000EFJ, GSE165895, GSE138405, GSE101921, GSE206145-NatGen2015, GSE120943, GSE98367, ENCSR193NSH, GSE206145, ENCSR981FDC, ENCSR000BMY, ENCSR635OSG, ENCSR767DFK, ENCSR984DZW, ENCSR495WGO, ENCSR853VWZ, GSE111913, ENCSR335RKQ, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE126990, GSE50893, ENCSR000ECS
  • Cell type: Liver, HuCC-T1, RPE, Fibroblast, HeLa-S3, IMR-90, K-562, GM18486, HFFc6, Monocytes, GM12878, SK-N-SH, RT-112, Macrophage, MCF-7, Hela-Kyoto, Hep-G2, A-549, HCAEC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 13% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.789
  • Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: True
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 72% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 37%, "5_TxWk": 27%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, PGR, HMG20A, ZSCAN5C, E2F7, XBP1, PATZ1, FOXA1, RXRB, KDM3A, ATF3, NFIC, ZBTB44, PRDM1, DPF1, HDAC3, CDX2, ZNF467, ZNF629, TEAD1, TRIM28, KLF6, ZNF217, ESR1, HNF1B, USF2, JUN, TCF12, CTCF, BAF155, EP300, KLF1, MNT, SOX5, GATA6, DPF2, PAX8, PRDM4, SMC1, FOXA3, ZNF175, GATAD2A, TFAP2C, MLX, GLIS1, NANOG, POU2F2, BRD3, MYCN, TOP2A, ZBTB17, ZBTB48, STAT1, GATAD1, SAP130, ARID3A, TBP, HNF4G, HOXC5, ERG, ZBTB21, ZNF341, ONECUT1, MYC, HOMEZ, RAD21, FOXP2, GRHL3, RXRA, GABPA, STAT3, NKX3-1, ZNF398, RCOR1, NFE2, MIER3, NR2F6, NR3C1, ESRRA, CEBPB, CREB1, TBL1XR1, GRHL2, FEZF1, TRPS1, GABPB1, SPI1, TFE3, MIXL1, IRF1, HDAC2, GATA2, FLI1, ZGPAT, MXI1, NFIL3, ZNF554, RUNX1, THAP11, BCL6, CEBPA, NKX2-2, EZH2phosphoT487, ZNF335, SOX13, AFF4, SIN3A, CBX8, PRDM10, MYBL2, RARA, CREBBP, ZNF35, ZNF384, RUNX2, GATA4, OSR2, ZNF184, PBX4, NFIB, ARNT, ZEB2, SMAD4, PBX3, FOXJ2, FOS, MED1, TEAD3, PIAS1, NR1H2, SREBF2, USF1, SP1, TFAP2A, HNF4A, IKZF5, REST, ARID1A, ZBTB7A, ZHX1, ASH2L, PHIP, FOXP1, PRDM6, SMC3, ELL2, STAG1, SKI, PPARG, FOXA2, CHD2, ZNF692, ZSCAN16, WT1, ZNF30, GTF2B, FOXF1, ZBTB33, HOXB13, KDM1A, YY1, RELA, ZNF148, BRG1, HIF1A, GATA3, TAL1, MAX, NRIP1, GATA1, TLE3, KLF4, CEBPG, NCOA3, NR2F2, ZNF512, TCF7L2, ZNF334, BRD2, ELF3, ARRB1, BHLHE40, AR, NFKBIZ, TAF1, ZNF324, EGLN2, ZNF366, EGR1, RNF2, JUND, BRD4, MAZ, BRCA1, AHR
  • Target gene symbol (double-evidenced CRMs): MAP3K7CL,TIAM1,GRIK1,CCT8,BACH1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 514
  • Number of somatic mutations (non-coding): 46
  • Related genes and loops
  • Related gene: ENSG00000156261, ENSG00000156265, ENSG00000156273, ENSG00000171189, ENSG00000156299,
  • Related loop: chr21:29075000-29100000~~chr21:29175000-29200000, chr21:29124718-29126312~~chr21:29176363-29177502, chr21:29150000-29175000~~chr21:29275000-29300000, chr21:29150000-29175000~~chr21:29325000-29350000, chr21:29150000-29175000~~chr21:29350000-29375000, chr21:29150000-29175000~~chr21:29475000-29500000, chr21:29150000-29175000~~chr21:29825000-29850000, chr21:29150000-29175000~~chr21:30175000-30200000, chr21:29175000-29200000~~chr21:29275000-29300000, chr21:29175000-29200000~~chr21:29300000-29325000, chr21:29175000-29200000~~chr21:29350000-29375000, chr21:29175000-29200000~~chr21:31250000-31275000, chr21:29181177-29183351~~chr21:29297767-29300990, chr21:29181313-29182963~~chr21:29347735-29349361,
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