- Basic information
- CohesinDB ID: CDBP00416146
- Locus: chr21-29177913-29178352
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Data sourse: GSE138405, ENCSR230ZWH
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Cell type: Liver, Hela-Kyoto
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
72% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 55%,
"5_TxWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, POU2F2, BCL6, MEF2B, CHD8, SMC1A, EBF1, FOXA2, ZNF335, PPARG, POU5F1, XBP1, ZBTB17, ZBTB48, HNF1A, MTA2, FOXA1, ZFX, ERG, YY1, RELA, KDM1A, RUNX2, MYC, RAD21, RUNX3, GRHL3, HIF1A, RXRA, PROX1, NKX2-1, GABPA, MECOM, MAX, ZNF143, IKZF1, CDX2, NR3C1, KLF4, CEBPB, NCOA3, ZEB1, KLF5, TEAD1, KLF6, TCF7L2, ZMYM3, EZH2, TP53, OCA2, HNF1B, USF2, EBF3, ELF3, CTCF, USF1, SPI1, BCL11A, JUN, SP1, AR, IRF1, HNF4A, BAF155, EP300, FLI1, RAD51, BRD4, SMARCA5, BCOR, FOXP1, SCRT1, MAZ, ZNF623, TFAP2C
- Target gene symbol (double-evidenced CRMs): CCT8,TIAM1,BACH1,MAP3K7CL
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156261,
ENSG00000156265,
ENSG00000156273,
ENSG00000156299,
- Related loop:
chr21:29075000-29100000~~chr21:29175000-29200000,
chr21:29124718-29126312~~chr21:29176363-29177502,
chr21:29150000-29175000~~chr21:29275000-29300000,
chr21:29150000-29175000~~chr21:29325000-29350000,
chr21:29150000-29175000~~chr21:29350000-29375000,
chr21:29150000-29175000~~chr21:29475000-29500000,
chr21:29150000-29175000~~chr21:29825000-29850000,
chr21:29150000-29175000~~chr21:30175000-30200000,
chr21:29175000-29200000~~chr21:29275000-29300000,
chr21:29175000-29200000~~chr21:29300000-29325000,
chr21:29175000-29200000~~chr21:29350000-29375000,
chr21:29175000-29200000~~chr21:31250000-31275000,
chr21:29181177-29183351~~chr21:29297767-29300990,
chr21:29181313-29182963~~chr21:29347735-29349361,