Deatailed information for cohesin site CDBP00416149

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  • Basic information
  • CohesinDB ID: CDBP00416149
  • Locus: chr21-29192039-29192372
  • Data sourse: GSE206145-NatGen2015, ENCSR153HNT, GSE86191
  • Cell type: K-562, Fibroblast, HCT-116
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: SA1,Rad21,SA2
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: TSS
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 72% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 58%, "5_TxWk": 32%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, FOXA1, HLF, RXRB, MLL4, HDGF, PAX5, TEAD1, ZNF121, E2F5, LMO2, OCA2, MED26, PITX3, ZNF561, E4F1, SOX5, ZNF528, KMT2B, GATAD2A, NANOG, POU5F1, BRD3, CTBP1, STAT1, SAP130, ERG, ZBTB21, ZNF597, NFKB2, SMARCA4, FOXK2, ZNF398, RCOR1, NR2F6, CD74, CEBPB, CREB1, GABPB1, ZHX2, ELF4, MIXL1, KLF17, GATA2, ZNF644, FLI1, HCFC1, NR2C2, RELB, RUNX1, CEBPA, HDAC1, SP5, TRIM22, SMARCC1, PRDM10, ZNF549, ZXDC, ZBTB2, ELK1, ZBTB10, ATF2, FOXM1, GMEB1, PML, PIAS1, SMAD1, NR1H2, C11orf30, EVI1, STAT5A, IKZF5, RBM25, AFF1, ELL2, ETV4, NFATC3, MEF2B, CBX3, CREM, CHD2, ZSCAN16, WT1, MEF2C, NEUROD1, JUNB, TCF4, ZFP36, BATF, SPIB, KLF4, ZFP69B, ZBTB6, MED, ELF3, ARID4B, RXR, EGLN2, ZNF366, HSF1, NCOR1, ZBTB26, SCRT1, ILF3, ZNF316, FOSL1, SMARCA2, ZNF660, XBP1, PBX2, ATF3, ZFP64, RUNX3, CBFB, ZSCAN4, BACH2, ZNF467, MAF, JMJD1C, ELF1, SNAI2, KLF10, JUN, CTCF, MNT, DPF2, IRF4, ZNF350, TFAP2C, RBPJ, ZSCAN21, ZBTB17, ZBTB48, MTA2, ZNF317, SRF, NBN, CHD4, ONECUT1, HOMEZ, FOXP2, RXRA, NKX3-1, MIER3, LEF1, VDR, NR3C1, ESRRA, KMT2A, TBL1XR1, KLF8, GRHL2, EBF3, SMARCA5, NFIL3, THAP11, ZBTB24, SOX13, AFF4, ZNF18, SP3, ARNT, DAXX, BACH1, ZEB2, NFYA, PBX3, ETV6, HMGXB4, TEAD3, ZXDB, ZNF680, KLF9, USF1, SP1, BCL11A, ATF7, ASH2L, CTBP2, SMC3, MLLT1, STAG1, STAG2, ZNF394, MTA3, EBF1, MEIS1, MAFF, ESR2, ZNF580, KLF7, ZKSCAN1, KDM1A, BCL3, KAT2B, ZNF830, GATA3, TAL1, NRIP1, ZNF143, MTA1, ZNF768, TP53, ZNF334, NFKB1, ZSCAN22, PHOX2B, BRD2, KAT8, TBX21, EGR1, RNF2, IKZF2, BRD4, JUND, CUX1, IRF9, PGR, CBX5, SOX2, PATZ1, BMI1, CHD7, ATF4, ZNF189, SMARCE1, KLF6, NFE2L2, ZNF217, ESR1, KLF1, SOX4, TRIM24, ZNF92, GLIS1, POU2F2, ELK4, SP4, TBP, HOXC5, SMARCC2, ETS1, MYC, ARID1B, NKX2-1, GABPA, STAT3, IKZF1, DNMT3B, EZH2, ZNF652, SPI1, HDAC2, INTS13, NCOA2, ZNF554, ETV5, BCL6, SIN3A, ERG3, MEF2A, MYBL2, RARA, CREBBP, ZNF35, ZNF384, SMAD4, ZNF518A, CDK8, ZEB1, SPDEF, ZMYM3, NCOA1, MAFK, NR4A1, HNF4A, REST, ARID1A, ZHX1, HNRNPLL, BCOR, FOXP1, NCOR2, PPARG, ZNF692, GTF2B, ZNF30, ZNF574, TCF7, ZNF318, RELA, TARDBP, CHAMP1, SKIL, MAX, GFI1B, NR2F1, TCF7L2, KDM5B, PKNOX1, MYOD1, T, AR, ZBTB16, YAP1, ZNF324, ZZZ3, AHR, FOSL2, DMAP1, HMG20A, E2F7, MEIS2, SUZ12, ZNF529, NFIC, ZNF362, CTCFL, PRDM1, MECOM, CDX2, ZNF629, KLF5, TRIM28, BCLAF1, ETV1, RCOR2, HNF1B, MLL, TCF12, BAF155, EP300, GATA6, SOX6, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EHMT2, EED, CHD8, MYCN, RUNX1T1, MLLT3, GATAD1, ARID3A, ZNF341, RAD21, GRHL3, PROX1, APC, ZNF614, XRCC5, NFE2, TCF25, ZNF639, ARNTL, TRPS1, HES1, TFE3, EHF, IRF1, ZGPAT, MRTFB, ATF1, CBX1, MAFG, SMC1A, ZFX, SMAD3, CBX8, TWIST1, IRF2, NOTCH1, BRD9, RUNX2, CDK6, GATA4, OSR2, ZNF184, NRF1, PBX4, NR2C1, FOS, MED1, CEBPD, MYB, SCRT2, VEZF1, ZNF3, L3MBTL2, SETDB1, KLF16, NIPBL, ZBTB7A, PHIP, TCF3, SKI, PAX7, ZNF283, FOXA2, E2F8, ZNF600, ZBED1, CDK9, HOXB13, YY1, ZNF148, HIF1A, OTX2, GATA1, HAND2, CEBPG, SP7, NCOA3, NR2F2, ZNF687, NFKBIZ, BHLHE40, TAF1, ZBTB40, MYNN, NOTCH3, MAZ, ZNF24
  • Target gene symbol (double-evidenced CRMs): CCT8,TIAM1,MAP3K7CL,BACH1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 4
  • Related genes and loops
  • Related gene: ENSG00000156261, ENSG00000156265, ENSG00000156273, ENSG00000156299,
  • Related loop: chr21:29075000-29100000~~chr21:29175000-29200000, chr21:29175000-29200000~~chr21:29275000-29300000, chr21:29175000-29200000~~chr21:29300000-29325000, chr21:29175000-29200000~~chr21:29350000-29375000, chr21:29175000-29200000~~chr21:31250000-31275000, chr21:29195502-29197292~~chr21:29297767-29300990,
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