Deatailed information for cohesin site CDBP00416150

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  • Basic information
  • CohesinDB ID: CDBP00416150
  • Locus: chr21-29192661-29199386
  • Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR000DYE, ENCSR917QNE, GSE93080, GSE67783, GSE86191, GSE101921, GSE120943, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, ENCSR247LSH, GSE105004, ENCSR676MJK, GSE155324, ENCSR054FKH, GSE83726, GSE126755, ENCSR748MVX, ENCSR000ECS, GSE131577, ENCSR000BLD, GSE104888, GSE103477, GSE108869, GSE138405, GSE135093, ENCSR193NSH, GSE206145, GSE85526, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, GSE129526, ENCSR537EFT, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE76893, GSE76815, ENCSR000BMY, ENCSR000EHX, GSE97394, ENCSR217ELF, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, ENCSR481YWD, GSE73207, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE105028, ENCSR000EDW, GSE165895, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR807WAC, ENCSR495WGO, ENCSR853VWZ, ENCSR956LGB, ENCSR153HNT, GSE68388, GSE126990
  • Cell type: MDM, RH4, GM10847, GM2610, SLK, GM19240, OCI-AML-3, HSPC, Liver, HuCC-T1, B-cell, H9-hESC, GM2630, RPE, Fibroblast, HEKn, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, DKO, HFFc6, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Lymphoblast, TF-1, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, THP-1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, A-549, HUVEC, HCAEC, GM19238, HeLa, Neutrophil, GM18951
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 58% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.322
  • Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TSS,Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 72% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "7_Enh": 28%, "15_Quies": 27%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: ESRRA, KDM5B, SMAD3, GRHL2, STAT3, ZNF143
  • Target gene symbol (double-evidenced CRMs): TIAM1,BACH1,MAP3K7CL,CCT8
  • Function elements
  • Human SNPs: Myocardial_infarction
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 8
  • Related genes and loops
  • Related gene: ENSG00000156261, ENSG00000156265, ENSG00000156273, ENSG00000156299,
  • Related loop: chr21:17700000-17725000~~chr21:29200000-29225000, chr21:29075000-29100000~~chr21:29175000-29200000, chr21:29075000-29100000~~chr21:29200000-29225000, chr21:29175000-29200000~~chr21:29275000-29300000, chr21:29175000-29200000~~chr21:29300000-29325000, chr21:29175000-29200000~~chr21:29350000-29375000, chr21:29175000-29200000~~chr21:31250000-31275000, chr21:29195502-29197292~~chr21:29297767-29300990,
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