Deatailed information for cohesin site CDBP00416153


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  • Basic information
  • CohesinDB ID: CDBP00416153
  • Locus: chr21-29207162-29210453
  • Data sourse: ENCSR000EFJ, ENCSR000EAC, ENCSR230ZWH, GSE98367, GSE165895, ENCSR000HPG, ENCSR000BLY, GSE206145, GSE206145-NatGen2015, GSE62063, ENCSR000BMY, GSE120943, GSE103477, GSE131606, GSE108869, ENCSR917QNE
  • Cell type: MDM, RPE, Fibroblast, Monocytes, GM12878, Ramos, DKO, HeLa-S3, IMR-90, SK-N-SH, Liver, Macrophage, HFFc6
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 10% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.856
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 72% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 57%, "7_Enh": 24%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: RUNX1, NFATC3, PGR, CTNNB1, MEF2B, FOXA2, SMC1A, ZNF425, TOP2A, SOX2, E2F8, MTA2, DUX4, STAT1, FOXA1, NBN, TRIM22, HOXB13, ERG, HOXC5, RELA, TARDBP, BMI1, RUNX2, CDK6, GATA4, MYC, RUNX3, PBX4, ARNT, DAXX, HIF1A, GRHL3, BACH1, OTX2, GABPA, BATF, IKZF1, ELF1, TRIM28, NR2F1, SMAD1, ZMYM3, ZNF217, ZNF687, ESR1, LMO2, ZNF334, TCF12, BAF155, EP300, TBX21, BHLHE40, AR, SPI1, DPF2, GATA2, GATAD2B, ATF7, ASH2L, RAD51, IKZF2, BRD4, SMARCA5, FOXP1, RELB, MLLT1
  • Target gene symbol (double-evidenced CRMs): MAP3K7CL,CCT8
  • Function elements
  • Human SNPs: Liver_enzyme_levels_(alanine_transaminase)
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops

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