- Basic information
- CohesinDB ID: CDBP00416155
- Locus: chr21-29213561-29214401
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Data sourse: GSE120943, ENCSR153HNT, GSE98367
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Cell type: K-562, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
72% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 73%,
"5_TxWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF621, NME2, XBP1, FOXA1, SUZ12, HDGF, ZNF274, ZBTB5, ZNF444, ZSCAN4, CDC5L, MYOG, BCLAF1, OCA2, USF2, ZIK1, CTCF, TCF12, KLF1, E4F1, ZBTB20, DPF2, PAX8, TRIM24, IRF4, GLI4, ZNF528, EHMT2, TFAP2C, EED, POU2F2, CHD8, ZSCAN5D, MYCN, ZNF239, TOP2A, CTBP1, ZNF317, ZSCAN21, ZBTB48, ZSCAN5A, SRF, DDX5, ERG, ZNF114, MCM5, MYC, SMARCA4, GRHL3, FOXK2, ZNF398, IKZF1, ZNF639, CREB1, YBX3, EZH2, ARHGAP35, SPI1, IRF1, HDAC2, SSRP1, GATAD2B, ZNF146, ZNF785, SMARCA5, SALL2, BCL6, CEBPA, HDAC1, ZNF707, CRY1, ZFX, ZNF534, ZNF747, ZNF473, NFXL1, MCM2, ZNF18, RUNX2, OSR2, ZNF280C, NFIB, ZBTB10, ZNF48, ZNF670, KLF16, ARID2, ZNF548, BCOR, SMC3, STAG1, MLLT1, ZNF394, NCOA4, FOXA2, ZNF600, ZNF692, ZNF662, YY2, ZKSCAN1, YY1, RELA, TARDBP, ZNF148, ZNF266, ZNF155, ZNF521, MCM3, HIF1A, ZNF311, TAL1, ZNF143, ZSCAN26, GATA1, ZFP69B, NCOA3, ZNF544, ZNF791, ZNF334, CLOCK, MAZ, ZSCAN23, ZNF24
- Target gene symbol (double-evidenced CRMs): MAP3K7CL,CCT8
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops