Deatailed information for cohesin site CDBP00416157
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- Basic information
- CohesinDB ID: CDBP00416157
- Locus: chr21-29220845-29223441
- Data sourse: ENCSR000EFJ, GSE67783, GSE86191, ENCSR000HPG, ENCSR879KXD, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE68388, GSE73207, GSE116344, GSE165895
- Cell type: RPE, Fibroblast, HCT-116, RH4, TF-1, IMR-90, K-562, HSPC, HuCC-T1, HFFc6
- DNA Sequence of binding site: UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
- CTCF binding site: CTCF CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
- Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
- Compartment: 72% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 70%,
"7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2). - Co-bound Transcriptional factors: FOSL1, ZNF660, ZSCAN5C, XBP1, PATZ1, PBX2, ZFHX2, ATF3, INSM2, CHD7, ZBTB44, RUNX3, PRDM1, CBFB, ZNF189, SMARCE1, ZSCAN4, HDAC3, ZNF629, TEAD1, ZNF121, TRIM28, ETV1, NFE2L2, KLF10, SMAD5, ESR1, OCA2, TP73, ZNF561, CTCF, JUN, TCF12, EP300, ZBTB20, DPF2, TRIM24, SOX6, E2F1, TEAD4, ZNF175, EED, GLIS1, POU2F2, CHD8, ZSCAN5D, ID3, CTBP1, ZSCAN21, ZBTB17, ZNF317, ZBTB48, MTA2, ZMYND8, ZBTB21, ZBTB8A, MYC, SMARCA4, ZNF2, TSHZ1, ARID1B, RAD21, GRHL3, STAT3, APC, ZNF398, IKZF1, NFE2, RCOR1, ZNF639, NR2F6, ARNTL, NR3C1, CEBPB, CREB1, TBL1XR1, EZH2, KLF8, FEZF1, ZHX2, HES1, GATA2, ZNF554, ATF1, RUNX1, HDAC1, CRY1, ZNF335, ZFX, SMAD3, ZMIZ1, PRDM10, MEF2A, CREBBP, ZNF35, RUNX2, OSR2, ZNF184, SP3, HMGB2, PRDM9, ZNF518A, ZEB2, CBFA2T3, PBX3, ZNF10, FOS, CDK8, FOXM1, MED1, ZEB1, DIDO1, ZNF558, ZXDB, SCRT2, PML, SUPT16H, KLF16, MAFK, BCL11A, NR4A1, ZBTB7A, GLI2, ATF7, PHIP, PRDM6, ZNF623, SMC3, STAG1, ZNF394, CBFA2T2, CREM, SS18, ZNF600, ZNF692, ZSCAN16, ZNF30, WT1, ESR2, ZNF574, ZNF318, KDM1A, YY1, RELA, JUNB, ZIC2, GATA3, TAL1, MAX, GATA1, ZNF143, ZFP69B, SP7, GFI1B, ZKSCAN8, NR2F1, NEUROG2, TP53, ZBTB6, MYOD1, EGR2, BRD2, ZNF843, BHLHE40, PAX3-FOXO1, AR, YAP1, ZNF324, ZNF366, ZBTB42, RNF2, NCOR1, SCRT1, JUND, BRD4, NOTCH3, CUX1, MAZ, ZSCAN23, MEF2D, ZNF24, FOSL2
- Target gene symbol (double-evidenced CRMs): CCT8,MAP3K7CL
- Function elements
- Human SNPs: Response_to_mTOR_inhibitor_(everolimus)
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene: ENSG00000156261, ENSG00000156265,
- Related loop: chr21:17700000-17725000~~chr21:29200000-29225000, chr21:25450000-25475000~~chr21:29225000-29250000, chr21:29075000-29100000~~chr21:29200000-29225000, chr21:29162246-29165257~~chr21:29217358-29218786, chr21:29225000-29250000~~chr21:29325000-29350000, chr21:29225000-29250000~~chr21:29350000-29375000,
Tools:
- Assay
