- Basic information
- CohesinDB ID: CDBP00416178
- Locus: chr21-29281119-29281788
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Data sourse: GSE206145-GSE177045, GSE86191, GSE138405, GSE111913, GSE206145-NatGen2015, ENCSR000EDE
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Cell type: MCF-7, Hela-Kyoto, Fibroblast, HCT-116, HeLa-S3, RT-112
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SMC1,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 95%,
"9_Het": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, CTNNB1, CEBPA, FOXA2, HMG20A, SOX13, ZFX, STAT1, FOXA1, HLF, ZNF770, HOXB13, PRDM10, ERG, MYC, GATA4, RAD21, TCF4, ARNT, GATA3, GABPA, STAT3, NKX3-1, GATA1, CDX2, TLE3, CEBPB, CREB1, PIAS1, ETV1, ESR1, BAF155, NIPBL, EP300, HNF4A, AR, GATA6, SOX5, ZNF579, GATA2, TRIM24, BRD4, FOXP1, NCOR2, GATAD2A, AHR
- Target gene symbol (double-evidenced CRMs): MAP3K7CL,CCT8,TIAM1,GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156261,
ENSG00000156265,
ENSG00000171189,
ENSG00000156299,
- Related loop:
chr21:29075000-29100000~~chr21:29275000-29300000,
chr21:29100000-29125000~~chr21:29275000-29300000,
chr21:29150000-29175000~~chr21:29275000-29300000,
chr21:29175000-29200000~~chr21:29275000-29300000,
chr21:29275000-29300000~~chr21:29675000-29700000,
chr21:29275000-29300000~~chr21:29800000-29825000,
chr21:29275000-29300000~~chr21:31150000-31175000,