- Basic information
- CohesinDB ID: CDBP00416201
- Locus: chr21-29334032-29336486
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR000FAD, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR917QNE, ENCSR000EFJ, GSE115602, GSE165895, GSE143937, GSE93080, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE101921, GSE135093, GSE206145-NatGen2015, GSE120943, GSE138105, ENCSR703TNG, GSE116344, GSE98367, ENCSR879KXD, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000EHX, GSE97394, GSE55407, ENCSR000BTQ, GSE129526, ENCSR000HPG, GSE111913, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE126990, GSE50893, ENCSR000ECS, GSE73207
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Cell type: MDM, RH4, GM2610, SLK, Liver, HuCC-T1, H9-hESC, RPE, GM2630, HMEC, Fibroblast, HeLa-S3, IMR-90, K-562, HFFc6, H1-hESC, Monocytes, TF-1, GM12878, GM2588, SK-N-SH, RT-112, THP-1, Macrophage, HUES64, MCF-7, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, OCI-AML-3
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 26% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.656
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 55%,
"7_Enh": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, CHD8, FOXA2, BRD3, EBF1, TEAD4, ZNF600, XBP1, ZBTB17, SMAD3, ZBTB48, WT1, FOXA1, ZBTB33, MEF2C, ZNF300, ERG, MEF2A, RELA, ZNF384, JUNB, ATF3, RUNX2, MYC, NFIC, OSR2, GATA4, RAD21, ZNF362, PBX4, BACH1, RXRA, NKX2-1, GATA3, PRDM9, GABPA, ZNF189, TAL1, MAX, PBX3, STAT3, SUPT5H, GATA1, FOS, MED1, VDR, NR3C1, MAF, CEBPB, TEAD1, TRIM28, SUPT16H, MLL, HNF1B, FEZF1, EBF3, ZFP91, BRD2, ZHX2, RBM22, SPI1, EP300, JUN, TCF12, BCL11A, GATA2, FLI1, HSF1, BRD4, JUND, E2F1, MRTFB, SMC3, ZNF24, FOSL2
- Target gene symbol (double-evidenced CRMs): MAP3K7CL,BACH1,CCT8
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 24
- Number of somatic mutations (non-coding): 0
- Related genes and loops