- Basic information
- CohesinDB ID: CDBP00416205
- Locus: chr21-29340708-29341150
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Data sourse: GSE206145-NatGen2015, GSE62063, GSE98367
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Cell type: Fibroblast, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,Mau2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 66%,
"7_Enh": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, ZSCAN5C, E2F7, MEIS2, XBP1, PATZ1, FOXA1, LEO1, PBX2, ZFHX2, ATF3, NFIC, HMGB2, RUNX3, PRDM1, CHD7, ZNF487, CBFB, ZNF273, ZNF189, PAX5, ZSCAN4, ZNF629, MAF, TEAD1, TRIM28, BCLAF1, ETV1, ELF1, KLF10, ESR1, OCA2, JUN, TCF12, CTCF, BAF155, KLF1, EP300, GATA6, DPF2, SOX4, SIX5, IRF4, TRIM24, RFX5, E2F1, SMC1, TEAD4, GATAD2A, TFAP2C, EED, GLIS1, NANOG, CHD8, POU2F2, ZNF263, MYCN, TOP2A, POU5F1, ZSCAN21, ZBTB17, DUX4, ZBTB48, STAT1, SRF, ARID3A, ERG2, ERG, HOXC5, ZBTB21, ZNF597, NFKB2, ETS1, ONECUT1, MYC, EOMES, SMARCA4, TSHZ1, RAD21, FOXP2, RXRA, BATF3, GABPA, STAT3, ZNF398, IKZF1, RCOR1, ZNF639, VDR, ARNTL, NR3C1, ESRRA, CEBPB, CREB1, EZH2, KLF8, BMPR1A, FEZF1, ZHX2, SPI1, EHF, IRF1, GATA2, FLI1, RELB, MRTFB, ZIM3, RUNX1, BCL6, SMC1A, CEBPA, MTA3, SIN3A, ZNF534, ZFX, ZNF335, AFF4, SMAD3, ZNF770, TET2, ERG3, ZNF18, PRDM10, SMARCC1, TWIST1, MEF2A, ZBTB2, NOTCH1, RUNX2, CDK6, GATA4, OSR2, ZNF184, SP3, PBX4, ARNT, DAXX, BACH1, ATF2, ZNF708, ZEB2, ZNF518A, PRDM9, PBX3, ETV6, ZNF10, CHD1, CDK8, FOS, FOXM1, SUPT5H, MED1, PML, ZXDB, ZNF558, SCRT2, PIAS1, MYB, SUPT16H, CEBPD, TBX5, KLF16, NUP98-HOXA9, RBM22, BCL11A, SP1, GSPT2, HNF4A, MAFK, USF1, REST, ATF7, ASH2L, HOXA9, PHIP, TCF3, FOXP1, PRDM6, SMC3, PPARG, FOXA2, TBL1X, EBF1, HDAC6, CREM, NFATC1, ZNF600, ZNF692, GTF2B, WT1, ZBED1, ZSCAN16, FOXF1, PAF1, ZBTB33, TCF7, HOXB13, BCL3, KDM1A, ZNF19, YY1, RELA, NEUROD1, JUNB, ZIC2, HIF1A, OTX2, GATA3, BATF, TAL1, MAX, GATA1, ZNF143, AGO2, TLE3, CEBPG, BCL11B, SP7, NEUROG2, TP53, PKNOX1, ZNF334, NFKB1, MYOD1, EGR2, BRD2, ELF3, TBX21, BHLHE40, AR, TAF1, ZNF324, ZNF366, HEXIM1, ZBTB42, ZBTB26, NCOR1, IKZF2, JUND, BRD4, SCRT1, MAZ, ZSCAN23, BRCA1, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): CCT8,MAP3K7CL,BACH1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops