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Basic information

CohesinDB ID: CDBP00416211

Locus: chr21-29356096-29358712

Data sourse: ENCSR230ZWH, ENCSR000BKV, GSE67783, GSE98367, ENCSR879KXD, GSE120943, ENCSR153HNT, GSE73207, GSE103477, GSE50893, GSE126755, ENCSR917QNE

Cell type: MDM, Monocytes, TF-1, GM18486, K-562, Liver, Neutrophil, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.900

Subunit: SMC3,SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 68% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 63%, "15_Quies": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TP63, BCL11A

Target gene symbol (double-evidenced CRMs): MAP3K7CL,CCT8,GRIK1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 12

Related genes and loops

Related gene: ENSG00000156261, ENSG00000156265, ENSG00000171189,

eachgene

Deatailed information for cohesin site CDBP00416211