Browse_each

Basic information

CohesinDB ID: CDBP00416212

Locus: chr21-29359610-29363005

Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, ENCSR000FAD, GSE72082, ENCSR000BSB, ENCSR760NPX, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE131606, GSE108869, GSE25021, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE115602, ENCSR000EAC, GSE143937, GSE165895, ENCSR000BKV, GSE67783, GSE138405, GSE86191, GSE93080, GSE76893, GSE152721, ENCSR198ZYJ, GSE138105, GSE130135, ENCSR199XBQ, ENCSR703TNG, GSE116344, GSE145327, ENCSR895JMI, ENCSR000EEG, ENCSR193NSH, ENCSR879KXD, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR247LSH, ENCSR000BMY, ENCSR000EHX, ENCSR748MVX, ENCSR767DFK, ENCSR807WAC, ENCSR981FDC, ENCSR495WGO, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, GSE131956, GSE110061, GSE129526, ENCSR676MJK, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE83726, GSE126990, GSE50893, ENCSR000ECS

Cell type: RH4, SLK, HSPC, Liver, H9-hESC, RPE, GM2630, Ishikawa, HeLa-S3, GM2255, IMR-90, K-562, HFFc6, DKO, H1-hESC, GM12878, GM12891, GBM39, SK-N-SH, GM19193, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, Neurons-H1, A-549, GM19238, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 28% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.644

Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 68% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 49%, "4_Tx": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, SMC1A, FOXA2, ZNF263, POU5F1, XBP1, SMAD3, DUX4, FOXA1, SRF, TCF7, TRIM22, HOXB13, ERG, YY1, RELA, ZBTB2, ZNF384, ASCL1, ATF3, RUNX2, MYC, GATA4, RAD21, ARNT, TCF4, HIF1A, GATA3, GABPA, XRCC5, MAX, NKX3-1, FOS, SUPT5H, GATA1, HAND2, MED1, CDX2, NR3C1, PDX1, NCOA3, CREB1, TCF7L2, SMAD1, EZH2, KDM5B, ESR1, NR1H2, RUVBL1, CTCF, BCL11A, BAF155, BHLHE40, HNF4A, GATA2, REST, EGLN2, BRD4, ZNF440, SMC3, FOXA3, STAG1

Target gene symbol (double-evidenced CRMs): MAP3K7CL,GRIK1,CCT8

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 22

Related genes and loops

Related gene: ENSG00000156261, ENSG00000156265, ENSG00000171189,

eachgene

Deatailed information for cohesin site CDBP00416212