- Basic information
- CohesinDB ID: CDBP00416240
- Locus: chr21-29481578-29482796
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Data sourse: ENCSR000BLD, ENCSR000BKV, GSE86191, GSE105028, GSE206145-NatGen2015, GSE206145, ENCSR153HNT, GSE25021, GSE50893, GSE165895
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, GM19240, GM12891, K-562, HFFc6, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 73%,
"5_TxWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, POU2F2, FOXA2, XBP1, FOXA1, MEF2C, ZBTB33, ERG, RELA, RUNX2, ARNT, NKX2-1, BATF, NR3C1, CEBPB, TRIM28, CTCF, SPI1, BCL11A, AR, BRD4, ZNF24, FOSL2
- Target gene symbol (double-evidenced CRMs): CCT8,BACH1,MAP3K7CL,GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156261,
ENSG00000156265,
ENSG00000156273,
ENSG00000171189,
- Related loop:
chr21:29075000-29100000~~chr21:29475000-29500000,
chr21:29150000-29175000~~chr21:29475000-29500000,
chr21:29350000-29375000~~chr21:29475000-29500000,
chr21:29475000-29500000~~chr21:29625000-29650000,
chr21:29475000-29500000~~chr21:29675000-29700000,
chr21:29475000-29500000~~chr21:29800000-29825000,
chr21:29475000-29500000~~chr21:29825000-29850000,
chr21:29475000-29500000~~chr21:29850000-29875000,
chr21:29475000-29500000~~chr21:30175000-30200000,
chr21:29475000-29500000~~chr21:31075000-31100000,
chr21:29475283-29477626~~chr21:29848801-29851250,
chr21:29475354-29477955~~chr21:29848859-29851155,
chr21:29475484-29477685~~chr21:29848825-29851056,
chr21:29475491-29477670~~chr21:29848836-29851040,
chr21:29475518-29477669~~chr21:29848791-29850711,
chr21:29475529-29477666~~chr21:29848789-29851052,
chr21:29475556-29477615~~chr21:29777400-29779013,
chr21:29475556-29477615~~chr21:29848787-29851050,
chr21:29475556-29477615~~chr21:30043860-30045602,
chr21:29475563-29477677~~chr21:29848795-29851007,
chr21:29475564-29478019~~chr21:29848799-29851068,
chr21:29475568-29477653~~chr21:29848870-29851001,
chr21:29475596-29477667~~chr21:29848807-29850780,
chr21:29475599-29477637~~chr21:29848779-29850995,
chr21:29475623-29477670~~chr21:29848751-29851040,
chr21:29475637-29477601~~chr21:29848871-29851131,
chr21:29475638-29477575~~chr21:29848922-29850711,
chr21:29475657-29477582~~chr21:29849125-29850633,
chr21:29475737-29477633~~chr21:29816942-29818230,
chr21:29475737-29477633~~chr21:29848936-29850979,
chr21:29475742-29477425~~chr21:29848901-29851051,
chr21:29475742-29477624~~chr21:29848886-29851009,
chr21:29475747-29477623~~chr21:29848684-29850668,
chr21:29475760-29477668~~chr21:29848796-29851053,
chr21:29475785-29477407~~chr21:29848950-29851037,
chr21:29475789-29477163~~chr21:29848973-29850569,
chr21:29475804-29477615~~chr21:29848934-29850864,
chr21:29475820-29477664~~chr21:29848730-29850666,
chr21:29475835-29477612~~chr21:29848731-29851135,
chr21:29475896-29477736~~chr21:29848795-29851163,
chr21:29475897-29477591~~chr21:29848871-29851155,
chr21:29475899-29477659~~chr21:29848754-29850764,
chr21:29475923-29477211~~chr21:29849001-29850588,
chr21:29475929-29477624~~chr21:29848944-29851080,
chr21:29475936-29477231~~chr21:29848938-29850670,
chr21:29475948-29477521~~chr21:29848873-29851025,
chr21:29475991-29477541~~chr21:29849122-29850656,
chr21:29475998-29477588~~chr21:29848987-29850748,
chr21:29476019-29477393~~chr21:29849110-29850652,
chr21:29476020-29477392~~chr21:29849045-29850808,
chr21:29476020-29477530~~chr21:29849152-29850642,