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Basic information

CohesinDB ID: CDBP00416244

Locus: chr21-29498142-29498791

Data sourse: GSE206145-NatGen2015, GSE206145-GSE177045

Cell type: MCF-7, Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 68% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 63%, "9_Het": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, CBX5, ZNF660, SOX2, NME2, PATZ1, FOXA1, RXRB, ATF3, NFIC, ZFP64, CTCFL, CHD7, MXD4, MZF1, ZNF736, TEAD1, TRIM28, ZNF121, ZNF557, KLF6, NFE2L2, LMO2, ESR1, RCOR2, OCA2, CTCF, TCF12, JUN, EP300, BAF155, GATA6, SOX5, DPF2, TRIM24, RFX5, DEK, ZNF528, SMC1, ZNF280A, TEAD4, FOXA3, GATAD2A, RBPJ, TFAP2C, NANOG, CHD8, BRD1, ZSCAN5D, POU5F1, ZNF263, TOP2A, MYCN, ZSCAN21, ZNF317, ZBTB48, SRF, GATAD1, SAP130, ARID3A, SP4, ERG, HOXC5, USP7, HOMEZ, RAD21, RXRA, GABPA, STAT3, ZNF614, XRCC5, NKX3-1, IKZF1, MIER3, RCOR1, NFE2, NR2F6, ARNTL, VDR, CEBPB, CREB1, EZH2, GABPB1, ZHX2, SPI1, MIXL1, IRF1, HDAC2, ZNF644, MXD3, FLI1, DRAP1, ZGPAT, HCFC1, MRTFB, ZNF554, ETV5, CC2D1A, RUNX1, THAP11, CBX1, SMC1A, HDAC1, CEBPA, BCL6, SOX13, ZFX, AFF4, FIP1L1, SMAD3, ZNF654, ERG3, TRIM22, SMARCC1, PRDM10, TWIST1, ZNF701, ZBTB2, ZNF35, ZNF384, PRPF4, RUNX2, GATA4, ZNF184, NRF1, ZNF48, ATF2, ZEB2, SMAD4, NFYA, FOXM1, SP2, SMARCB1, CDK8, HMGXB4, CHD1, MED1, GMEB1, TEAD3, ZXDB, PIAS1, SMAD1, SETDB1, USF1, BCL11A, IKZF5, REST, ZNF479, ZBTB7A, ZHX1, HNRNPLL, FOXP1, SMC3, ELL2, STAG1, STAG2, PPARG, CBX3, TBL1X, AGO1, EBF1, WT1, ZNF574, ZBTB33, MEF2C, ZNF580, HOXB13, KDM1A, YY1, RELA, NEUROD1, CHAMP1, SP140, HIF1A, GATA3, ZNF519, BATF, MAX, GATA1, ZNF143, CEBPG, ZNF592, GFI1B, NCOA3, TCF7L2, KDM5B, TP53, ZNF334, ELF3, BRD2, KAT8, ARRB1, ARID4B, AR, EGR1, HSF1, NOTCH3, BRD4, JUND, MAZ, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): CCT8,MAP3K7CL,BACH1,GRIK1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156261, ENSG00000156265, ENSG00000156273, ENSG00000171189,

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Deatailed information for cohesin site CDBP00416244