- Basic information
- CohesinDB ID: CDBP00416280
- Locus: chr21-29658295-29660604
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Data sourse: ENCSR153HNT, ENCSR879KXD, GSE98367
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Cell type: K-562, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
37% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 70%,
"7_Enh": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBX5, CBX1, KLF13, CBX3, MTA3, ZNF316, XRCC3, ID3, ZNF317, FOXA1, ZBTB33, ZNF18, YY1, RELA, CHAMP1, ZNF24, ARNT, ZEB2, TAL1, FOXM1, NR2C1, ZNF143, IKZF1, NFRKB, ZNF592, NR2F2, TRIM28, ZKSCAN8, BCLAF1, EZH2, MLLT1, SETDB1, USF1, NR4A1, IRF1, PTRF, DPF2, REST, TRIM24, CREB3, DDX20, JUND, ZNF280A, TEAD4, ZNF175, ILK, EHMT2, CC2D1A, PTTG1
- Target gene symbol (double-evidenced CRMs): CCT8,MAP3K7CL,GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 168
- Number of somatic mutations (non-coding): 24
- Related genes and loops