- Basic information
- CohesinDB ID: CDBP00416282
- Locus: chr21-29667605-29667982
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Data sourse: ENCSR000BLD, ENCSR000BKV, GSE98367, ENCSR879KXD, GSE105028, GSE103477
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Cell type: H1-hESC, K-562, THP-1, Macrophage, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
37% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 84%,
"14_ReprPCWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, NFIA, SMC1A, MAFG, CBX3, MEF2B, EBF1, RBPJ, POU5F1, CHD8, XBP1, DUX4, FOXA1, MEF2C, BAHD1, HOXB13, KDM1A, YY1, RELA, NFIC, SMARCA4, RFX1, RAD21, GRHL3, ARNT, GATA3, MAX, SPIB, IKZF1, CDK8, NFE2, ZNF736, HAND2, BACH2, MITF, ZNF592, CEBPB, TRIM28, MYB, ETV1, TFAP2C, KMT2A, KDM5B, MLL, PITX3, USF2, PHOX2B, CTCF, USF1, SPI1, AR, GATA2, TRIM24, BRD4, TEAD4, KMT2B, ZNF175, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): CCT8,MAP3K7CL,GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 14
- Number of somatic mutations (non-coding): 0
- Related genes and loops