- Basic information
- CohesinDB ID: CDBP00416318
- Locus: chr21-29867790-29868026
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
28% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 85%,
"14_ReprPCWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, YBX1, NCOA4, SMC1A, HDAC1, FOXA2, TOP2A, SS18, NME2, MTA2, ASH1L, FOXA1, ZNF662, CBX8, HOXB13, ZNF596, ERG, ZBTB2, MYC, SMARCA4, ZNF184, MCM3, PRDM1, PHF21A, ARNT, SNIP1, PRDM9, PAX5, NKX3-1, MTA1, IKZF1, ZNF639, TLE3, CEBPG, CEBPB, THRAP3, ELF1, ZNF512, PIAS1, MLLT1, EZH2, ARHGAP35, GABPB1, NUP98-HOXA9, BAF155, AR, PYGO2, HDAC2, ARID2, GATA2, ARID1A, TRIM24, ZNF366, ZNF407, HSF1, RNF2, BCOR, FOXP1, ZNF280A, ZNF24, EHMT2
- Target gene symbol (double-evidenced CRMs): BACH1,MAP3K7CL,CCT8,GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 161
- Number of somatic mutations (non-coding): 0
- Related genes and loops