- Basic information
- CohesinDB ID: CDBP00416334
- Locus: chr21-30035043-30035297
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 83%,
"14_ReprPCWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CREBBP, MAF, CHD8, SMC1A, CEBPB, TOP2A, NME2, HSF1, ARNT, ESR1, PRDM1, SPI1
- Target gene symbol (double-evidenced CRMs): MAP3K7CL,GRIK1,CCT8
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 9
- Related genes and loops
- Related gene:
ENSG00000156261,
ENSG00000156265,
ENSG00000171189,
- Related loop:
chr21:29075000-29100000~~chr21:30025000-30050000,
chr21:29675000-29700000~~chr21:30025000-30050000,
chr21:29925000-29950000~~chr21:30025000-30050000,
chr21:30025000-30050000~~chr21:30175000-30200000,
chr21:30025000-30050000~~chr21:30250000-30275000,
chr21:30025000-30050000~~chr21:30400000-30425000,
chr21:30025000-30050000~~chr21:30500000-30525000,
chr21:30025000-30050000~~chr21:31075000-31100000,
chr21:30025000-30050000~~chr21:31600000-31625000,