- Basic information
- CohesinDB ID: CDBP00416348
- Locus: chr21-30191933-30192080
-
Data sourse: GSE120943, GSE98367
-
Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 91%,
"14_ReprPCWk": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NME2, HSF1, PRDM1, SETDB1, SUZ12
- Target gene symbol (double-evidenced CRMs): MAP3K7CL,BACH1,CCT8,GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000156261,
ENSG00000156265,
ENSG00000156273,
ENSG00000171189,
- Related loop:
chr21:26825000-26850000~~chr21:30175000-30200000,
chr21:29075000-29100000~~chr21:30175000-30200000,
chr21:29150000-29175000~~chr21:30175000-30200000,
chr21:29350000-29375000~~chr21:30175000-30200000,
chr21:29475000-29500000~~chr21:30175000-30200000,
chr21:29575000-29600000~~chr21:30175000-30200000,
chr21:29925000-29950000~~chr21:30175000-30200000,
chr21:29943210-29945043~~chr21:30193229-30195738,
chr21:29943256-29945015~~chr21:30194046-30195747,
chr21:29943274-29945035~~chr21:30193637-30195774,
chr21:29943381-29944811~~chr21:30194078-30195728,
chr21:29943482-29944650~~chr21:30194059-30195711,
chr21:29950000-29975000~~chr21:30175000-30200000,
chr21:30025000-30050000~~chr21:30175000-30200000,
chr21:30043489-30045655~~chr21:30194059-30195711,
chr21:30043634-30045679~~chr21:30194094-30195702,
chr21:30043637-30045675~~chr21:30194049-30195562,
chr21:30043752-30045664~~chr21:30194049-30195711,
chr21:30043756-30045614~~chr21:30193229-30195738,
chr21:30043767-30045627~~chr21:30193927-30195724,
chr21:30043827-30045692~~chr21:30193829-30195709,
chr21:30043955-30045406~~chr21:30194162-30195586,
chr21:30043991-30045406~~chr21:30194144-30195644,
chr21:30044042-30045658~~chr21:30194075-30195765,
chr21:30050000-30075000~~chr21:30175000-30200000,
chr21:30070984-30073381~~chr21:30193229-30195738,
chr21:30071517-30073936~~chr21:30193737-30195757,
chr21:30071583-30074009~~chr21:30193870-30195773,
chr21:30071597-30073842~~chr21:30194040-30195598,
chr21:30071749-30073856~~chr21:30194075-30195765,
chr21:30071750-30073955~~chr21:30193790-30195799,
chr21:30071825-30073458~~chr21:30194117-30195675,
chr21:30071865-30073462~~chr21:30193877-30195720,
chr21:30071886-30073585~~chr21:30194049-30195711,
chr21:30075000-30100000~~chr21:30175000-30200000,