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Basic information

CohesinDB ID: CDBP00416458

Locus: chr21-31078642-31079257

Data sourse: ENCSR000EAC, ENCSR000DZP, GSE155324, ENCSR000BMY, GSE50893

Cell type: GM12892, GM2630, GM2610, Lymphoblast, GM12878, GM12891, GM19238

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: SMC3,Rad21,SA1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 54% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 86%, "14_ReprPCWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, SMC1A, FOXA2, DUX4, STAT1, FOXA1, ERG, YY1, RELA, MYC, GATA4, RUNX3, ARNT, BATF3, BATF, PAX5, ZNF143, MED1, NR3C1, MAF, CEBPB, STAT5B, MYB, ESR1, CTCF, JUN, BCL11A, SPI1, TBX21, AR, GATA2, IRF4, HNRNPLL, RBPJ

Target gene symbol (double-evidenced CRMs): BACH1,KRTAP19-1,MAP3K7CL,TIAM1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 8

Related genes and loops

Related gene: ENSG00000156265, ENSG00000156273, ENSG00000184351, ENSG00000156299,

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Deatailed information for cohesin site CDBP00416458