Deatailed information for gene ENSG00000157551
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010108
- Gene Symbol: KCNJ15
- Ensembl ID: ENSG00000157551
-
Gene locus: chr21:38256740-38307357
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs
- Regulatory cohesin (double-evidenced):
chr21-36424574-36425739,
chr21-36426097-36426703,
chr21-36427097-36427532,
chr21-36428024-36432912,
chr21-36433833-36434412,
chr21-36435084-36436691,
chr21-36437128-36438862,
chr21-36439462-36440472,
chr21-36446479-36447042,
chr21-36448377-36448761,
chr21-36449284-36452157,
chr21-36499698-36502459,
chr21-36502665-36508046,
chr21-36508508-36509460,
chr21-36509687-36510756,
chr21-36511314-36511916,
chr21-36512825-36514000,
chr21-36514562-36514704,
chr21-36514932-36516116,
chr21-36516886-36517136,
chr21-36518707-36520114,
chr21-36522371-36522616,
chr21-36522943-36523216,
chr21-36523577-36525374,
chr21-37249994-37251771,
chr21-37254108-37254748,
chr21-37256946-37259141,
chr21-37259350-37259929,
chr21-37263577-37265365,
chr21-37265595-37269410,
chr21-37270551-37271438,
chr21-37271793-37272440,
chr21-37272945-37273597,
chr21-37274026-37274267,
chr21-37274761-37275372,
chr21-37351226-37351559,
chr21-37352423-37352964,
chr21-37356357-37357538,
chr21-37357896-37359418,
chr21-37361494-37361790,
chr21-37362970-37363891,
chr21-37364688-37373796,
chr21-37374041-37376667,
chr21-37729837-37730152,
chr21-37730892-37731148,
chr21-37735375-37735832,
chr21-37742634-37743029,
chr21-37746968-37747115,
chr21-37749181-37749550,
chr21-38124153-38130792,
chr21-38135930-38141562,
chr21-38147929-38148377,
chr21-38151064-38151512,
chr21-38155827-38157030,
chr21-38157453-38161826,
chr21-38165622-38167121,
chr21-38167829-38173299,
chr21-38173632-38174464,
chr21-38216497-38222875,
chr21-38252145-38252348,
chr21-38253333-38253633,
chr21-38255085-38256173,
chr21-38256759-38258229,
chr21-38258446-38259956,
chr21-38260291-38265425,
chr21-38265648-38270119,
chr21-38270636-38271112,
chr21-38271912-38272896,
chr21-38273791-38279650,
chr21-38280103-38280841,
chr21-38281812-38282342,
chr21-38282614-38284469,
chr21-38284801-38299034,
chr21-38299358-38300863,
chr21-38301072-38308873,
chr21-38309457-38313340,
chr21-38333133-38335676,
chr21-38750928-38753320,
chr21-38755256-38758111,
chr21-38758589-38759179,
chr21-38759468-38760630,
chr21-38761727-38762289,
chr21-38762803-38763102,
chr21-38764079-38764735,
chr21-38765117-38765356,
chr21-38766557-38767917,
chr21-38768383-38770086,
chr21-38771502-38771829,
chr21-38772380-38772727,
chr21-38772940-38775249,
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Co-expression with cohesin genes Rho = 0.0570
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.814
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
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Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.855
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: HEK293T,GM12891,GM12878,RT-112,Skin-Fibroblast,A-549,GM19238,HFFc6,H9-hESC
- Related loop:
chr21:31275000-31300000~~chr21:38250000-38275000,
chr21:34525000-34550000~~chr21:38275000-38300000,
chr21:36075000-36100000~~chr21:38250000-38275000,
chr21:36425000-36450000~~chr21:38300000-38325000,
chr21:36500000-36525000~~chr21:38250000-38275000,
chr21:37250000-37275000~~chr21:38250000-38275000,
chr21:37350000-37375000~~chr21:38275000-38300000,
chr21:37725000-37750000~~chr21:38300000-38325000,
chr21:38125000-38150000~~chr21:38250000-38275000,
chr21:38125000-38150000~~chr21:38275000-38300000,
chr21:38150000-38175000~~chr21:38250000-38275000,
chr21:38217588-38220774~~chr21:38306391-38309235,
chr21:38218492-38220499~~chr21:38268300-38270566,
chr21:38218530-38220189~~chr21:38267684-38270477,
chr21:38218546-38219987~~chr21:38269172-38270349,
chr21:38250000-38275000~~chr21:38750000-38775000,
chr21:38269135-38270391~~chr21:38333337-38334718,
chr21:38289123-38290768~~chr21:38302683-38304165,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
GSE44267, ENCSR244BBG, ENCSR662QKG, ENCSR732QOH, ENCSR299VMZ, Direct, ENCSR527RXH, 4DNFIFLJLIS5, GSE105028, 4DNFI1UEG1HD, 4DNFI5SUHCGZ, GSE155380, ENCSR981FNA, 4DNFII84FBKM, ENCSR410MDC
- Cohesin-loop subunit: Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: SLK,OCI-AML-3,K-562,MCF-10A,Keratinocytes,CordBlood
- Cohesin-DEGs, number of studies: 11
- Cohesin-DEGs, study: GSE83870,GSE73224,GSE111537,GSE101921,GSE154086,GSE131448,GSE138937
- Cohesin-DEGs, subunit: SMC3,SA2,CTCF,SMC1,Rad21