- Basic information
- CohesinDB ID: CDBP00415324
- Locus: chr21-25866908-25867564
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Data sourse: GSE126634, GSE152721
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Cell type: HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 80%,
"5_TxWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NANOG, CHD8, BRD1, POU2F2, POU5F1, SOX2, GTF2B, SMARCC1, ZNF384, NOTCH1, CHD7, ARNT, GRHL3, NKX2-1, RCOR1, TEAD1, ZBTB40, POU2F3, FOXP1, TEAD4, TFAP2C
- Target gene symbol (double-evidenced CRMs): CYYR1,GABPA,MRPL39,APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000154727,
ENSG00000142192,
ENSG00000166265,
- Related loop:
chr21:25421231-25422782~~chr21:25861820-25863486,
chr21:25600000-25625000~~chr21:25850000-25875000,
chr21:25606735-25609548~~chr21:25871125-25872823,
chr21:25606776-25609578~~chr21:25861792-25863529,
chr21:25606789-25609441~~chr21:25861500-25863573,
chr21:25606803-25609752~~chr21:25861575-25863761,
chr21:25606815-25609560~~chr21:25861600-25863597,
chr21:25606816-25609496~~chr21:25861723-25863498,
chr21:25606871-25609531~~chr21:25861792-25863454,
chr21:25606873-25609559~~chr21:25861596-25863488,
chr21:25606887-25609611~~chr21:25861935-25863735,
chr21:25606899-25609820~~chr21:25861786-25863545,
chr21:25606914-25609560~~chr21:25871146-25873235,
chr21:25606943-25609746~~chr21:25861950-25863530,
chr21:25606945-25609755~~chr21:25861950-25863417,
chr21:25607003-25609546~~chr21:25862121-25863346,
chr21:25607005-25609570~~chr21:25861550-25863545,
chr21:25607533-25609506~~chr21:25862107-25863351,
chr21:25750000-25775000~~chr21:25850000-25875000,
chr21:25789469-25791355~~chr21:25861621-25863550,
chr21:25789550-25791386~~chr21:25861500-25863573,
chr21:25789570-25791547~~chr21:25861792-25863529,
chr21:25850000-25875000~~chr21:26175000-26200000,
chr21:25850000-25875000~~chr21:26325000-26350000,
chr21:25850000-25875000~~chr21:26450000-26475000,
chr21:25850000-25875000~~chr21:26675000-26700000,
chr21:25850000-25875000~~chr21:26700000-26725000,
chr21:25862108-25863550~~chr21:26715501-26718096,
chr21:25871157-25873150~~chr21:26715252-26718261,