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Basic information

CohesinDB ID: CDBP00415335

Locus: chr21-25898579-25899047

Data sourse: GSE116344

Cell type: RH4

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 55%, "4_Tx": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, CBX5, PGR, LCORL, MEIS2, XBP1, FOXA1, PBX2, HNRNPK, ATF3, NFIC, ZNF362, ZBTB44, CHD7, TP63, ZNF467, MYOG, ELF1, BCLAF1, TRIM28, TEAD1, ESR1, ZFP91, CTCF, JUN, BAF155, IRF4, RFX5, SMC1, TEAD4, PDX1, POU2F2, CHD8, POU5F1, TOP2A, RUNX1T1, STAT1, ZNF205, SRF, DDX5, ARID3A, HOXC5, ERG, OGG1, MYC, SMARCA4, RAD21, RXRA, GABPA, STAT3, NKX3-1, RCOR1, DACH1, CEBPB, CREB1, EZH2, EBF3, ZHX2, SPI1, GATA2, FLI1, RELB, MRTFB, NCOA2, RUNX1, MAFG, SMC1A, CBX1, NKX2-2, POU4F2, SMAD3, ZNF654, TRIM22, SMARCC1, ZBTB2, RUNX2, GATA4, ZNF184, ARNT, NFIB, ATF2, HMBOX1, PBX3, MAFB, FOS, CDK8, MED1, CEBPD, PIAS1, SMAD1, C11orf30, RBM22, MAFK, SP1, BCL11A, REST, ZBTB7A, POU2F3, ATF7, FOXP1, SMC3, STAG1, STAG2, FOXA2, EBF1, MEIS1, PAF1, GTF2B, MAFF, CDK9, HOXB13, YY1, RELA, JUNB, ISL1, HIF1A, OTX2, GATA3, BATF, TAL1, MAX, NRIP1, ZNF143, AGO2, HAND2, KLF4, CEBPG, SP7, GFI1B, NCOA3, TCF7L2, TP53, PKNOX1, ZNF334, ZSCAN22, PHOX2B, ELF3, BHLHE40, AR, ZBTB16, NOTCH3, BRD4, TBX2, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): ADAMTS1,CYYR1,MRPL39,APP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 8

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000154719, ENSG00000142192, ENSG00000166265, ENSG00000154734,

Tools:

Assay

refGene

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Cohesin site CDBP00415335

CDBP00415335 regulated genes

Related cohesin loop

Deatailed information for cohesin site CDBP00415335

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